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Drug repurposing screens reveal cell-type-specific entry pathways and FDA-approved drugs active against SARS-Cov-2.
Dittmar, Mark; Lee, Jae Seung; Whig, Kanupriya; Segrist, Elisha; Li, Minghua; Kamalia, Brinda; Castellana, Lauren; Ayyanathan, Kasirajan; Cardenas-Diaz, Fabian L; Morrisey, Edward E; Truitt, Rachel; Yang, Wenli; Jurado, Kellie; Samby, Kirandeep; Ramage, Holly; Schultz, David C; Cherry, Sara.
Afiliación
  • Dittmar M; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Lee JS; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Whig K; Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, PA, USA.
  • Segrist E; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Li M; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Kamalia B; Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, PA, USA.
  • Castellana L; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Ayyanathan K; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Cardenas-Diaz FL; Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Morrisey EE; Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Truitt R; Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Yang W; Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
  • Jurado K; Department of Microbiology, University of Pennsylvania, Philadelphia, PA, USA.
  • Samby K; Medicines for Malaria Venture, Geneva, Switzerland.
  • Ramage H; Department of Microbiology, Thomas Jefferson University, Philadelphia, PA, USA. Electronic address: holly.ramage@jefferson.edu.
  • Schultz DC; Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, PA, USA. Electronic address: dschultz@upenn.edu.
  • Cherry S; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia, PA, USA; Department of Microbiology, University of Pennsylvania, Philadelphia, PA, USA. Electronic address: cherrys
Cell Rep ; 35(1): 108959, 2021 04 06.
Article en En | MEDLINE | ID: mdl-33811811
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Ciclosporina / Células Epiteliales / Reposicionamiento de Medicamentos / SARS-CoV-2 / Tratamiento Farmacológico de COVID-19 / Pulmón Límite: Animals / Humans País/Región como asunto: America do norte Idioma: En Revista: Cell Rep Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Ciclosporina / Células Epiteliales / Reposicionamiento de Medicamentos / SARS-CoV-2 / Tratamiento Farmacológico de COVID-19 / Pulmón Límite: Animals / Humans País/Región como asunto: America do norte Idioma: En Revista: Cell Rep Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos