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iPSC modeling of stage-specific leukemogenesis reveals BAALC as a key oncogene in severe congenital neutropenia.
Dannenmann, Benjamin; Klimiankou, Maksim; Oswald, Benedikt; Solovyeva, Anna; Mardan, Jehan; Nasri, Masoud; Ritter, Malte; Zahabi, Azadeh; Arreba-Tutusaus, Patricia; Mir, Perihan; Stein, Frederic; Kandabarau, Siarhei; Lachmann, Nico; Moritz, Thomas; Morishima, Tatsuya; Konantz, Martina; Lengerke, Claudia; Ripperger, Tim; Steinemann, Doris; Erlacher, Miriam; Niemeyer, Charlotte M; Zeidler, Cornelia; Welte, Karl; Skokowa, Julia.
Afiliación
  • Dannenmann B; Department of Oncology, Hematology, Immunology, and Rheumatology, University Hospital Tuebingen, 72074 Tuebingen, Germany.
  • Klimiankou M; Department of Oncology, Hematology, Immunology, and Rheumatology, University Hospital Tuebingen, 72074 Tuebingen, Germany.
  • Oswald B; Department of Oncology, Hematology, Immunology, and Rheumatology, University Hospital Tuebingen, 72074 Tuebingen, Germany.
  • Solovyeva A; Department of Oncology, Hematology, Immunology, and Rheumatology, University Hospital Tuebingen, 72074 Tuebingen, Germany.
  • Mardan J; Department of Oncology, Hematology, Immunology, and Rheumatology, University Hospital Tuebingen, 72074 Tuebingen, Germany.
  • Nasri M; Department of Oncology, Hematology, Immunology, and Rheumatology, University Hospital Tuebingen, 72074 Tuebingen, Germany.
  • Ritter M; Department of Oncology, Hematology, Immunology, and Rheumatology, University Hospital Tuebingen, 72074 Tuebingen, Germany.
  • Zahabi A; Department of Oncology, Hematology, Immunology, and Rheumatology, University Hospital Tuebingen, 72074 Tuebingen, Germany.
  • Arreba-Tutusaus P; Department of Oncology, Hematology, Immunology, and Rheumatology, University Hospital Tuebingen, 72074 Tuebingen, Germany.
  • Mir P; Department of Oncology, Hematology, Immunology, and Rheumatology, University Hospital Tuebingen, 72074 Tuebingen, Germany.
  • Stein F; Department of Oncology, Hematology, Immunology, and Rheumatology, University Hospital Tuebingen, 72074 Tuebingen, Germany.
  • Kandabarau S; Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology (IKP), 70376 Stuttgart, Germany.
  • Lachmann N; Institute of Experimental Hematology, Hannover Medical School, 30625 Hannover, Germany.
  • Moritz T; Institute of Experimental Hematology, Hannover Medical School, 30625 Hannover, Germany.
  • Morishima T; Department of Oncology, Hematology, Immunology, and Rheumatology, University Hospital Tuebingen, 72074 Tuebingen, Germany.
  • Konantz M; Department of Biomedicine, University Hospital Basel, 4031 Basel, Switzerland.
  • Lengerke C; Department of Oncology, Hematology, Immunology, and Rheumatology, University Hospital Tuebingen, 72074 Tuebingen, Germany; Department of Biomedicine, University Hospital Basel, 4031 Basel, Switzerland.
  • Ripperger T; Institute of Human Genetics, Hannover Medical School, 30625 Hannover, Germany.
  • Steinemann D; Institute of Human Genetics, Hannover Medical School, 30625 Hannover, Germany.
  • Erlacher M; Faculty of Medicine, Division of Pediatric Hematology and Oncology Medical Center, Department of Pediatrics and Adolescent Medicine, University of Freiburg, 79106 Freiburg, Germany; German Cancer Consortium (DKTK), 79106 Freiburg, Germany; German Cancer Research Center (DKFZ), 69120 Heidelberg, Germ
  • Niemeyer CM; Faculty of Medicine, Division of Pediatric Hematology and Oncology Medical Center, Department of Pediatrics and Adolescent Medicine, University of Freiburg, 79106 Freiburg, Germany; German Cancer Consortium (DKTK), 79106 Freiburg, Germany; German Cancer Research Center (DKFZ), 69120 Heidelberg, Germ
  • Zeidler C; Department of Oncology, Hematology, Immunology and Bone Marrow Transplantation, Hannover Medical School, 39625 Hannover, Germany.
  • Welte K; University Children's Hospital Tuebingen, 72074 Tuebingen, Germany.
  • Skokowa J; Department of Oncology, Hematology, Immunology, and Rheumatology, University Hospital Tuebingen, 72074 Tuebingen, Germany. Electronic address: julia.skokowa@med.uni-tuebingen.de.
Cell Stem Cell ; 28(5): 906-922.e6, 2021 05 06.
Article en En | MEDLINE | ID: mdl-33894142
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Leucemia Mieloide Aguda / Células Madre Pluripotentes Inducidas / Proteínas de Neoplasias / Neutropenia Límite: Humans Idioma: En Revista: Cell Stem Cell Año: 2021 Tipo del documento: Article País de afiliación: Alemania
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Leucemia Mieloide Aguda / Células Madre Pluripotentes Inducidas / Proteínas de Neoplasias / Neutropenia Límite: Humans Idioma: En Revista: Cell Stem Cell Año: 2021 Tipo del documento: Article País de afiliación: Alemania