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A phase I study assessing the safety, tolerability, immunogenicity, and low-density lipoprotein cholesterol-lowering activity of immunotherapeutics targeting PCSK9.
Zeitlinger, Markus; Bauer, Martin; Reindl-Schwaighofer, Roman; Stoekenbroek, Robert M; Lambert, Gilles; Berger-Sieczkowski, Evelyn; Lagler, Heimo; Oesterreicher, Zoe; Wulkersdorfer, Beatrix; Lührs, Petra; Galabova, Gergana; Schwenke, Carsten; Mader, Robert M; Medori, Rossella; Landlinger, Christine; Kutzelnigg, Alexandra; Staffler, Günther.
Afiliación
  • Zeitlinger M; Department of Clinical Pharmacology, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.
  • Bauer M; Department of Clinical Pharmacology, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.
  • Reindl-Schwaighofer R; Department of Clinical Pharmacology, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.
  • Stoekenbroek RM; Department of Vascular Surgery, Academic Medical Center, University of Amsterdam, P.O. Box 22660, 1100 DD, Amsterdam, Netherlands.
  • Lambert G; Laboratoire Inserm, UMR 1188 DéTROI, Université de La Réunion, 2 Rue Maxime Rivière, 97490, Sainte Clotilde, France.
  • Berger-Sieczkowski E; Department of Neurology, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.
  • Lagler H; Department of Medicine I, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.
  • Oesterreicher Z; Department of Clinical Pharmacology, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.
  • Wulkersdorfer B; Department of Clinical Pharmacology, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.
  • Lührs P; AFFiRiS AG, Karl Farkas Gasse 22, 1030, Vienna, Austria.
  • Galabova G; AFFiRiS AG, Karl Farkas Gasse 22, 1030, Vienna, Austria.
  • Schwenke C; Origenis GmbH, Am Klopferspitz 19a, 82152, Martinsried, Germany.
  • Mader RM; SCO:SSiS, Karmeliterweg 42, 13465, Berlin, Germany.
  • Medori R; Department of Medicine I, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.
  • Landlinger C; AFFiRiS AG, Karl Farkas Gasse 22, 1030, Vienna, Austria.
  • Kutzelnigg A; AFFiRiS AG, Karl Farkas Gasse 22, 1030, Vienna, Austria.
  • Staffler G; AFFiRiS AG, Karl Farkas Gasse 22, 1030, Vienna, Austria.
Eur J Clin Pharmacol ; 77(10): 1473-1484, 2021 Oct.
Article en En | MEDLINE | ID: mdl-33969434
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Vacunas de Subunidad / Proproteína Convertasa 9 / Hipercolesterolemia Tipo de estudio: Clinical_trials Límite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Eur J Clin Pharmacol Año: 2021 Tipo del documento: Article País de afiliación: Austria
Texto completo
Imprimir
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PubMed Links
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Vacunas de Subunidad / Proproteína Convertasa 9 / Hipercolesterolemia Tipo de estudio: Clinical_trials Límite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Eur J Clin Pharmacol Año: 2021 Tipo del documento: Article País de afiliación: Austria