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Structural insight into SARS-CoV-2 neutralizing antibodies and modulation of syncytia.
Asarnow, Daniel; Wang, Bei; Lee, Wen-Hsin; Hu, Yuanyu; Huang, Ching-Wen; Faust, Bryan; Ng, Patricia Miang Lon; Ngoh, Eve Zi Xian; Bohn, Markus; Bulkley, David; Pizzorno, Andrés; Ary, Beatrice; Tan, Hwee Ching; Lee, Chia Yin; Minhat, Rabiatul Adawiyah; Terrier, Olivier; Soh, Mun Kuen; Teo, Frannie Jiuyi; Yeap, Yvonne Yee Chin; Seah, Shirley Gek Kheng; Chan, Conrad En Zuo; Connelly, Emily; Young, Nicholas J; Maurer-Stroh, Sebastian; Renia, Laurent; Hanson, Brendon John; Rosa-Calatrava, Manuel; Manglik, Aashish; Cheng, Yifan; Craik, Charles S; Wang, Cheng-I.
Afiliación
  • Asarnow D; Department of Biochemistry and Biophysics, University of California, San Francisco (UCSF) School of Medicine, San Francisco, CA, USA; QBI COVID-19 Research Group (QCRG), San Francisco, CA, USA.
  • Wang B; Singapore Immunology Network, Agency for Science, Technology and Research (A(∗)STAR), 8A Biomedical Grove, Immunos, Singapore 138648, Singapore.
  • Lee WH; Singapore Immunology Network, Agency for Science, Technology and Research (A(∗)STAR), 8A Biomedical Grove, Immunos, Singapore 138648, Singapore.
  • Hu Y; Singapore Immunology Network, Agency for Science, Technology and Research (A(∗)STAR), 8A Biomedical Grove, Immunos, Singapore 138648, Singapore.
  • Huang CW; Singapore Immunology Network, Agency for Science, Technology and Research (A(∗)STAR), 8A Biomedical Grove, Immunos, Singapore 138648, Singapore.
  • Faust B; Department of Biochemistry and Biophysics, University of California, San Francisco (UCSF) School of Medicine, San Francisco, CA, USA; QBI COVID-19 Research Group (QCRG), San Francisco, CA, USA.
  • Ng PML; Singapore Immunology Network, Agency for Science, Technology and Research (A(∗)STAR), 8A Biomedical Grove, Immunos, Singapore 138648, Singapore.
  • Ngoh EZX; Singapore Immunology Network, Agency for Science, Technology and Research (A(∗)STAR), 8A Biomedical Grove, Immunos, Singapore 138648, Singapore.
  • Bohn M; QBI COVID-19 Research Group (QCRG), San Francisco, CA, USA; Department of Pharmaceutical Chemistry, University of California, San Francisco (UCSF), San Francisco, CA, USA.
  • Bulkley D; Department of Biochemistry and Biophysics, University of California, San Francisco (UCSF) School of Medicine, San Francisco, CA, USA; QBI COVID-19 Research Group (QCRG), San Francisco, CA, USA.
  • Pizzorno A; CIRI, Centre International de Recherche en Infectiologie (Team VirPath), Université de Lyon, INSERM U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, 69007 Lyon, France.
  • Ary B; QBI COVID-19 Research Group (QCRG), San Francisco, CA, USA; Department of Pharmaceutical Chemistry, University of California, San Francisco (UCSF), San Francisco, CA, USA.
  • Tan HC; Singapore Immunology Network, Agency for Science, Technology and Research (A(∗)STAR), 8A Biomedical Grove, Immunos, Singapore 138648, Singapore.
  • Lee CY; Singapore Immunology Network, Agency for Science, Technology and Research (A(∗)STAR), 8A Biomedical Grove, Immunos, Singapore 138648, Singapore.
  • Minhat RA; Singapore Immunology Network, Agency for Science, Technology and Research (A(∗)STAR), 8A Biomedical Grove, Immunos, Singapore 138648, Singapore.
  • Terrier O; CIRI, Centre International de Recherche en Infectiologie (Team VirPath), Université de Lyon, INSERM U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, 69007 Lyon, France.
  • Soh MK; Singapore Immunology Network, Agency for Science, Technology and Research (A(∗)STAR), 8A Biomedical Grove, Immunos, Singapore 138648, Singapore.
  • Teo FJ; Singapore Immunology Network, Agency for Science, Technology and Research (A(∗)STAR), 8A Biomedical Grove, Immunos, Singapore 138648, Singapore.
  • Yeap YYC; Singapore Immunology Network, Agency for Science, Technology and Research (A(∗)STAR), 8A Biomedical Grove, Immunos, Singapore 138648, Singapore.
  • Seah SGK; Biological Defence Program, DSO National Laboratories, 27 Medical Drive, Singapore 117510, Singapore.
  • Chan CEZ; Biological Defence Program, DSO National Laboratories, 27 Medical Drive, Singapore 117510, Singapore.
  • Connelly E; Department of Pharmaceutical Chemistry, University of California, San Francisco (UCSF), San Francisco, CA, USA.
  • Young NJ; Department of Pharmaceutical Chemistry, University of California, San Francisco (UCSF), San Francisco, CA, USA.
  • Maurer-Stroh S; Bioinformatics Institute, Agency for Science, Technology and Research (A(∗)STAR), 30 Biopolis Street, Matrix, Singapore 138671, Singapore; Infectious Diseases Laboratories (ID Labs), Agency for Science, Technology and Research (A(∗)STAR), 8A Biomedical Grove, Immunos, Singapore 138648, S
  • Renia L; Singapore Immunology Network, Agency for Science, Technology and Research (A(∗)STAR), 8A Biomedical Grove, Immunos, Singapore 138648, Singapore; Infectious Diseases Laboratories (ID Labs), Agency for Science, Technology and Research (A(∗)STAR), 8A Biomedical Grove, Immunos, Singapore 138
  • Hanson BJ; Biological Defence Program, DSO National Laboratories, 27 Medical Drive, Singapore 117510, Singapore.
  • Rosa-Calatrava M; CIRI, Centre International de Recherche en Infectiologie (Team VirPath), Université de Lyon, INSERM U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, 69007 Lyon, France; VirNext, Faculté de Médecine RTH Laennec, Université Claude Bernard Lyon 1, Université de Lyon, Lyon, France.
  • Manglik A; QBI COVID-19 Research Group (QCRG), San Francisco, CA, USA; Department of Pharmaceutical Chemistry, University of California, San Francisco (UCSF), San Francisco, CA, USA; Department of Anesthesia and Perioperative Care, UCSF, San Francisco, CA, USA. Electronic address: aashish.manglik@ucsf.edu.
  • Cheng Y; Department of Biochemistry and Biophysics, University of California, San Francisco (UCSF) School of Medicine, San Francisco, CA, USA; QBI COVID-19 Research Group (QCRG), San Francisco, CA, USA; Howard Hughes Medical Institute, UCSF, San Francisco, CA, USA. Electronic address: ycheng@ucsf.edu.
  • Craik CS; QBI COVID-19 Research Group (QCRG), San Francisco, CA, USA; Department of Pharmaceutical Chemistry, University of California, San Francisco (UCSF), San Francisco, CA, USA. Electronic address: charles.craik@ucsf.edu.
  • Wang CI; Singapore Immunology Network, Agency for Science, Technology and Research (A(∗)STAR), 8A Biomedical Grove, Immunos, Singapore 138648, Singapore. Electronic address: wang_chengi@immunol.a-star.edu.sg.
Cell ; 184(12): 3192-3204.e16, 2021 06 10.
Article en En | MEDLINE | ID: mdl-33974910

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Células Gigantes / Anticuerpos Neutralizantes / Glicoproteína de la Espiga del Coronavirus Límite: Animals / Humans Idioma: En Revista: Cell Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Células Gigantes / Anticuerpos Neutralizantes / Glicoproteína de la Espiga del Coronavirus Límite: Animals / Humans Idioma: En Revista: Cell Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos