Inhibition of the Proliferation of Human Lung Fibroblasts by Prostacyclin Receptor Agonists is Linked to a Sustained cAMP Signal in the Nucleus.

Roberts, Maxine J; May, Lauren T; Keen, Alastair C; Liu, Bonan; Lam, Terrance; Charlton, Steven J; Rosethorne, Elizabeth M; Halls, Michelle L

Roberts, Maxine J; May, Lauren T; Keen, Alastair C; Liu, Bonan; Lam, Terrance; Charlton, Steven J; Rosethorne, Elizabeth M; Halls, Michelle L.

Afiliación

Roberts MJ; Cell Signalling Research Group, School of Life Sciences, University of Nottingham, Queen's Medical Centre, Nottingham, United Kingdom.
May LT; Drug Discovery Biology Theme, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Vic, Australia.
Keen AC; Drug Discovery Biology Theme, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Vic, Australia.
Liu B; Drug Discovery Biology Theme, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Vic, Australia.
Lam T; Drug Discovery Biology Theme, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Vic, Australia.
Charlton SJ; Drug Discovery Biology Theme, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Vic, Australia.
Rosethorne EM; Cell Signalling Research Group, School of Life Sciences, University of Nottingham, Queen's Medical Centre, Nottingham, United Kingdom.
Halls ML; Excellerate Bioscience Ltd., BioCity, Nottingham, United Kingdom.

Front Pharmacol ; 12: 669227, 2021.

Article en En | MEDLINE | ID: mdl-33995100

Palabras clave

G protein-coupled receptor; cAMP; extracellular signal-regulated kinase; localised signalling; prostacyclin receptor

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Revista: Front Pharmacol Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido

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