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Discovery of a simplified deguelin analog as an HSP90 C-terminal inhibitor for HER2-positive breast cancer.
Nguyen, Cong-Truong; Thanh La, Minh; Ann, Jihyae; Nam, Gibeom; Park, Hyun-Ju; Min Park, Jung; Kim, Yoon-Jae; Young Kim, Ji; Hong Seo, Jae; Lee, Jeewoo.
Afiliación
  • Nguyen CT; College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
  • Thanh La M; College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
  • Ann J; College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea.
  • Nam G; School of Pharmacy, Sungkyunkwan University, Suwon, Gyeonggi-do 16419, Republic of Korea.
  • Park HJ; School of Pharmacy, Sungkyunkwan University, Suwon, Gyeonggi-do 16419, Republic of Korea.
  • Min Park J; Division of Medical Oncology, Department of Internal Medicine, Korea University College of Medicine, Korea University, Seoul 08308, Republic of Korea; Brain Korea 21 Program for Biomedical Science, Korea University College of Medicine, Korea University, Seoul 08308, Republic of Korea.
  • Kim YJ; Division of Medical Oncology, Department of Internal Medicine, Korea University College of Medicine, Korea University, Seoul 08308, Republic of Korea; Brain Korea 21 Program for Biomedical Science, Korea University College of Medicine, Korea University, Seoul 08308, Republic of Korea; Department of
  • Young Kim J; Division of Medical Oncology, Department of Internal Medicine, Korea University College of Medicine, Korea University, Seoul 08308, Republic of Korea; Department of Biomedical Research Center, Korea University Guro Hospital, Korea University, Seoul 08308, Republic of Korea.
  • Hong Seo J; Division of Medical Oncology, Department of Internal Medicine, Korea University College of Medicine, Korea University, Seoul 08308, Republic of Korea; Brain Korea 21 Program for Biomedical Science, Korea University College of Medicine, Korea University, Seoul 08308, Republic of Korea.
  • Lee J; College of Pharmacy, Seoul National University, Seoul 08826, Republic of Korea. Electronic address: jeewoo@snu.ac.kr.
Bioorg Med Chem Lett ; 45: 128134, 2021 08 01.
Article en En | MEDLINE | ID: mdl-34044120
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Rotenona / Neoplasias de la Mama / Proteínas HSP90 de Choque Térmico / Descubrimiento de Drogas / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Female / Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2021 Tipo del documento: Article
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Rotenona / Neoplasias de la Mama / Proteínas HSP90 de Choque Térmico / Descubrimiento de Drogas / Antineoplásicos Tipo de estudio: Prognostic_studies Límite: Female / Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2021 Tipo del documento: Article