Inhibition effect of oxyepiberberine isolated from Coptis chinensis franch. On non-small cell lung cancer based on a network pharmacology approach and experimental validation.

Zhang, Ying; Yao, Yunfeng; Fu, Yingjie; Yuan, Zixin; Wu, Xingpan; Wang, Tianshun; Hong, Zongchao; Yang, Yanfang; Wu, Hezhen

Zhang, Ying; Yao, Yunfeng; Fu, Yingjie; Yuan, Zixin; Wu, Xingpan; Wang, Tianshun; Hong, Zongchao; Yang, Yanfang; Wu, Hezhen.

Afiliación

Zhang Y; Faculty of Pharmacy, Hubei University of Chinese Medicine, Wuhan, 430065, China.
Yao Y; Faculty of Pharmacy, Hubei University of Chinese Medicine, Wuhan, 430065, China.
Fu Y; Faculty of Pharmacy, Hubei University of Chinese Medicine, Wuhan, 430065, China.
Yuan Z; Faculty of Pharmacy, Hubei University of Chinese Medicine, Wuhan, 430065, China.
Wu X; Faculty of Pharmacy, Hubei University of Chinese Medicine, Wuhan, 430065, China.
Wang T; Faculty of Pharmacy, Hubei University of Chinese Medicine, Wuhan, 430065, China.
Hong Z; Faculty of Pharmacy, Hubei University of Chinese Medicine, Wuhan, 430065, China.
Yang Y; Faculty of Pharmacy, Hubei University of Chinese Medicine, Wuhan, 430065, China; Key Laboratory of Traditional Chinese Medicine Resources and Chemistry of Hubei Province, Wuhan, 430061, China. Electronic address: 1397@hbtcm.edu.cn.
Wu H; Faculty of Pharmacy, Hubei University of Chinese Medicine, Wuhan, 430065, China; Key Laboratory of Traditional Chinese Medicine Resources and Chemistry of Hubei Province, Wuhan, 430061, China. Electronic address: 1446@hbtcm.edu.cn.

J Ethnopharmacol ; 278: 114267, 2021 Oct 05.

Article en En | MEDLINE | ID: mdl-34087401

Asunto(s)

Antineoplásicos Fitogénicos/farmacología; Carcinoma de Pulmón de Células no Pequeñas/tratamiento farmacológico; Coptis chinensis/química; Neoplasias Pulmonares/tratamiento farmacológico; Células A549; Antineoplásicos Fitogénicos/aislamiento & purificación; Apoptosis/efectos de los fármacos; Carcinoma de Pulmón de Células no Pequeñas/patología; Línea Celular Tumoral; Proliferación Celular/efectos de los fármacos; Regulación Neoplásica de la Expresión Génica/efectos de los fármacos; Humanos; Neoplasias Pulmonares/patología; Simulación del Acoplamiento Molecular; Farmacología en Red

Palabras clave

Biological experimental; Cell proliferation; Coptis chinensis (Huanglian); NSCLC; Network pharmacology; Oxyepiberberine

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Carcinoma de Pulmón de Células no Pequeñas / Coptis chinensis / Neoplasias Pulmonares / Antineoplásicos Fitogénicos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: J Ethnopharmacol Año: 2021 Tipo del documento: Article País de afiliación: China

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google