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Gene-edited healthy donor CAR T cells show superior anti-tumour activity compared to CAR T cells derived from patients with lymphoma in an in vivo model of high-grade lymphoma.
Graham, Charlotte Elizabeth; Jozwik, Agnieszka; Quartey-Papafio, Ruby; Ioannou, Nikolaos; Metelo, Ana M; Scala, Carlo; Dickson, Glenda; Stewart, Orla; Almena-Carrasco, Maria; Peranzoni, Elisa; Ramsay, Alan G; Patten, Piers E M; Pertel, Thomas; Farzaneh, Farzin; Dupouy, Sandra; Pepper, Andrea; Benjamin, Reuben.
Afiliación
  • Graham CE; Faculty of Life Sciences and Medicine, School of Cancer and Pharmaceutical Sciences, King's College London, London, United Kingdom. charlotte.e.graham@kcl.ac.uk.
  • Jozwik A; King's College Hospital NHS Foundation Trust, London, United Kingdom. charlotte.e.graham@kcl.ac.uk.
  • Quartey-Papafio R; Faculty of Life Sciences and Medicine, School of Cancer and Pharmaceutical Sciences, King's College London, London, United Kingdom.
  • Ioannou N; Faculty of Life Sciences and Medicine, School of Cancer and Pharmaceutical Sciences, King's College London, London, United Kingdom.
  • Metelo AM; Faculty of Life Sciences and Medicine, School of Cancer and Pharmaceutical Sciences, King's College London, London, United Kingdom.
  • Scala C; Faculty of Life Sciences and Medicine, School of Cancer and Pharmaceutical Sciences, King's College London, London, United Kingdom.
  • Dickson G; Faculty of Life Sciences and Medicine, School of Cancer and Pharmaceutical Sciences, King's College London, London, United Kingdom.
  • Stewart O; Faculty of Life Sciences and Medicine, School of Cancer and Pharmaceutical Sciences, King's College London, London, United Kingdom.
  • Almena-Carrasco M; King's College Hospital NHS Foundation Trust, London, United Kingdom.
  • Peranzoni E; Institut de Recherches Internationales Servier, Paris, France.
  • Ramsay AG; Institut de Recherches Internationales Servier, Paris, France.
  • Patten PEM; Faculty of Life Sciences and Medicine, School of Cancer and Pharmaceutical Sciences, King's College London, London, United Kingdom.
  • Pertel T; Faculty of Life Sciences and Medicine, School of Cancer and Pharmaceutical Sciences, King's College London, London, United Kingdom.
  • Farzaneh F; King's College Hospital NHS Foundation Trust, London, United Kingdom.
  • Dupouy S; Allogene Therapeutics, San Francisco, CA, United States.
  • Pepper A; Faculty of Life Sciences and Medicine, School of Cancer and Pharmaceutical Sciences, King's College London, London, United Kingdom.
  • Benjamin R; Institut de Recherches Internationales Servier, Paris, France.
Leukemia ; 35(12): 3581-3584, 2021 12.
Article en En | MEDLINE | ID: mdl-34145373
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Inmunoterapia Adoptiva / Linfoma de Células B / Receptores de Antígenos de Linfocitos T alfa-beta / Antígenos CD19 / Edición Génica Límite: Animals / Humans Idioma: En Revista: Leukemia Asunto de la revista: HEMATOLOGIA / NEOPLASIAS Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Inmunoterapia Adoptiva / Linfoma de Células B / Receptores de Antígenos de Linfocitos T alfa-beta / Antígenos CD19 / Edición Génica Límite: Animals / Humans Idioma: En Revista: Leukemia Asunto de la revista: HEMATOLOGIA / NEOPLASIAS Año: 2021 Tipo del documento: Article País de afiliación: Reino Unido