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Dimethyl sulfoxide (DMSO) enhances direct cardiac reprogramming by inhibiting the bromodomain of coactivators CBP/p300.
Lim, Choon Kiat; Efthymios, Motakis; Tan, Wilson; Autio, Matias Ilmari; Tiang, Zenia; Li, Peter Yiqing; Foo, Roger Sik Yin.
Afiliación
  • Lim CK; Cardiovascular Research Institute, Yong Loo Lin School of Medicine, National University of Singapore, Centre for Translational Medicine, 14 Medical Drive, Singapore 117599, Singapore; Genome Institute of Singapore, 60 Biopolis Street, Singapore 138672, Singapore; NUS Graduate School of Integrative S
  • Efthymios M; Cardiovascular Research Institute, Yong Loo Lin School of Medicine, National University of Singapore, Centre for Translational Medicine, 14 Medical Drive, Singapore 117599, Singapore; Genome Institute of Singapore, 60 Biopolis Street, Singapore 138672, Singapore.
  • Tan W; Cardiovascular Research Institute, Yong Loo Lin School of Medicine, National University of Singapore, Centre for Translational Medicine, 14 Medical Drive, Singapore 117599, Singapore; Genome Institute of Singapore, 60 Biopolis Street, Singapore 138672, Singapore.
  • Autio MI; Genome Institute of Singapore, 60 Biopolis Street, Singapore 138672, Singapore.
  • Tiang Z; Cardiovascular Research Institute, Yong Loo Lin School of Medicine, National University of Singapore, Centre for Translational Medicine, 14 Medical Drive, Singapore 117599, Singapore; Genome Institute of Singapore, 60 Biopolis Street, Singapore 138672, Singapore.
  • Li PY; Cardiovascular Research Institute, Yong Loo Lin School of Medicine, National University of Singapore, Centre for Translational Medicine, 14 Medical Drive, Singapore 117599, Singapore.
  • Foo RSY; Cardiovascular Research Institute, Yong Loo Lin School of Medicine, National University of Singapore, Centre for Translational Medicine, 14 Medical Drive, Singapore 117599, Singapore; Genome Institute of Singapore, 60 Biopolis Street, Singapore 138672, Singapore. Electronic address: roger.foo@nus.ed
J Mol Cell Cardiol ; 160: 15-26, 2021 11.
Article en En | MEDLINE | ID: mdl-34146546

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Transducción de Señal / Dimetilsulfóxido / Miocitos Cardíacos / Factores de Transcripción p300-CBP / Reprogramación Celular / Fibroblastos / Dominios Proteicos Tipo de estudio: Guideline Límite: Animals / Pregnancy Idioma: En Revista: J Mol Cell Cardiol Año: 2021 Tipo del documento: Article

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Transducción de Señal / Dimetilsulfóxido / Miocitos Cardíacos / Factores de Transcripción p300-CBP / Reprogramación Celular / Fibroblastos / Dominios Proteicos Tipo de estudio: Guideline Límite: Animals / Pregnancy Idioma: En Revista: J Mol Cell Cardiol Año: 2021 Tipo del documento: Article