Exemestane encapsulated polymer-lipid hybrid nanoparticles for improved efficacy against breast cancer: optimization,<i>in vitro</i>characterization and cell culture studies.

Rizwanullah, Md; Perwez, Ahmad; Mir, Showkat Rasool; Alam Rizvi, Mohd Moshahid; Amin, Saima

Exemestane encapsulated polymer-lipid hybrid nanoparticles for improved efficacy against breast cancer: optimization,in vitrocharacterization and cell culture studies.

Rizwanullah, Md; Perwez, Ahmad; Mir, Showkat Rasool; Alam Rizvi, Mohd Moshahid; Amin, Saima.

Afiliación

Rizwanullah M; Formulation Research Lab, Department of Pharmaceutics, School of Pharmaceutical Education and Research (SPER), Jamia Hamdard, New Delhi-110062, India.
Perwez A; Genome Biology Lab, Department of Biosciences, Faculty of Natural Sciences, Jamia Millia Islamia, New Delhi-110025, India.
Mir SR; Phytopharmaceutical Laboratory, Department of Pharmacognosy and Phytochemistry, School of Pharmaceutical Education and Research (SPER), Jamia Hamdard, New Delhi-110062, India.
Alam Rizvi MM; Genome Biology Lab, Department of Biosciences, Faculty of Natural Sciences, Jamia Millia Islamia, New Delhi-110025, India.
Amin S; Formulation Research Lab, Department of Pharmaceutics, School of Pharmaceutical Education and Research (SPER), Jamia Hamdard, New Delhi-110062, India.

Nanotechnology ; 32(41)2021 Jul 20.

Article en En | MEDLINE | ID: mdl-34198267

Asunto(s)

Androstadienos/farmacología; Antineoplásicos/farmacología; Portadores de Fármacos/síntesis química; Composición de Medicamentos/métodos; Liposomas/química; Nanopartículas/química; Androstadienos/metabolismo; Antineoplásicos/metabolismo; Materiales Biomiméticos/química; Supervivencia Celular/efectos de los fármacos; Liberación de Fármacos; Estabilidad de Medicamentos; Análisis Factorial; Colorantes Fluorescentes/química; Jugo Gástrico/química; Humanos; Cinética; Liposomas/ultraestructura; Células MCF-7; Nanopartículas/ultraestructura; Fosfatidilcolinas/química; Poliésteres/química; Rodaminas/química; Vitamina E/química

Palabras clave

BoxBehnken design; breast cancer; cellular uptake; cytotoxicity; exemestane; polymer-lipid hybrid nanoparticles

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Portadores de Fármacos / Composición de Medicamentos / Nanopartículas / Androstadienos / Liposomas / Antineoplásicos Límite: Humans Idioma: En Revista: Nanotechnology Año: 2021 Tipo del documento: Article País de afiliación: India

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