Natural selection at work? Vitamin D deficiency rates and rising health problems in young Turkish Cypriot professionals.
Cent Eur J Public Health
; 29(2): 130-133, 2021 06.
Article
en En
| MEDLINE
| ID: mdl-34245553
ABSTRACT
OBJECTIVES:
Vitamin D is a fat-soluble, prohormone vitamin that is important especially for bone mineralization and skeletal health. In recent years, vitamin D deficiency appeared as a worldwide problem, affecting many people in different ways including the Northern Cypriot population. The deficiency might be caused by the lack of exposure to sunlight, diet low in vitamin D, sedentary lifestyle, and also due to some genetic variations in the vitamin D receptor (VDR) gene.METHODS:
In this study, four common VDR polymorphisms and associations with vitamin D deficiency in the Turkish Cypriot population between ages 18-40 and working in office conditions was studied by PCR- RFLP analysis.RESULTS:
rs2228570 C>T variant was shown to be significantly associated with low serum vitamin D levels in the studied population.CONCLUSION:
Together with the effect of rs2228570 C>T variant in the VDR gene, it is thought that the lifestyle changes in the Turkish Cypriot population might have caused the increased frequency of vitamin D deficiency in the young professionals.Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Deficiencia de Vitamina D
/
Polimorfismo de Nucleótido Simple
Tipo de estudio:
Observational_studies
/
Risk_factors_studies
Límite:
Adolescent
/
Adult
/
Humans
Idioma:
En
Revista:
Cent Eur J Public Health
Asunto de la revista:
EPIDEMIOLOGIA
/
SAUDE PUBLICA
Año:
2021
Tipo del documento:
Article
País de afiliación:
Turquía