Immune response of ponies to experimental infection with Ehrlichia equi.
Am J Vet Res
; 39(1): 15-8, 1978 Jan.
Article
en En
| MEDLINE
| ID: mdl-343663
ABSTRACT
Four ponies experimentally infected with Ehrlichia equi developed substantial cell-mediated immune responses, as measured by the leukocyte migration-inhibition test. Serum anti-E equi antibodies up to 11,280 were demonstrated by the indirect fluorescent antibody test. Cell-mediated immune responses returned to a base-line value by day 200 after primary inoculation, but serum antibody titers persisted for at least 300 days after inoculation. Two additional susceptible ponies, which were inoculated with convalescent blood or organ homogenates from ponies recovered from acute equine ehrlichiosis, treated with tetracycline, and subsequently challenge exposed with E equi-infective blood, did not develop clinical disease. This study suggested that ponies are resistant to reinfection with E equi following clinical ehrlichiosis.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Infecciones por Rickettsiaceae
/
Enfermedades de los Caballos
Límite:
Animals
Idioma:
En
Revista:
Am J Vet Res
Año:
1978
Tipo del documento:
Article