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Nicotinamide N-methyltransferase upregulation via the mTORC1-ATF4 pathway activation contributes to palmitate-induced lipotoxicity in hepatocytes.
Griffiths, Alexandra; Wang, Jun; Song, Qing; Iyamu, Iredia D; Liu, Lifeng; Park, Jooman; Jiang, Yuwei; Huang, Rong; Song, Zhenyuan.
Afiliación
  • Griffiths A; Department of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, Illinois.
  • Wang J; Department of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, Illinois.
  • Song Q; Department of Gastroenterology, Tongji Medical College and The Central Hospital of Wuhan, Huazhong University of Science and Technology, Wuhan, People's Republic of China.
  • Iyamu ID; Department of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, Illinois.
  • Liu L; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, Indiana.
  • Park J; Department of Physiology and Biophysics, University of Illinois at Chicago, Chicago, Illinois.
  • Jiang Y; Department of Physiology and Biophysics, University of Illinois at Chicago, Chicago, Illinois.
  • Huang R; Department of Physiology and Biophysics, University of Illinois at Chicago, Chicago, Illinois.
  • Song Z; Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, Indiana.
Am J Physiol Cell Physiol ; 321(3): C585-C595, 2021 09 01.
Article en En | MEDLINE | ID: mdl-34378991
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Palmitatos / Hepatocitos / Nicotinamida N-Metiltransferasa / Factor de Transcripción Activador 4 / Diana Mecanicista del Complejo 1 de la Rapamicina Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Am J Physiol Cell Physiol Asunto de la revista: FISIOLOGIA Año: 2021 Tipo del documento: Article
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Palmitatos / Hepatocitos / Nicotinamida N-Metiltransferasa / Factor de Transcripción Activador 4 / Diana Mecanicista del Complejo 1 de la Rapamicina Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Am J Physiol Cell Physiol Asunto de la revista: FISIOLOGIA Año: 2021 Tipo del documento: Article