Silver Nanoparticles Induce Time- and Tissue-Specific Genotoxicity in Oreochromis niloticus: Utilizing the Adsorptive Capacities of Fruit Peels to Minimize Genotoxicity.
Bull Environ Contam Toxicol
; 108(2): 300-308, 2022 Feb.
Article
en En
| MEDLINE
| ID: mdl-34379139
ABSTRACT
Fish were exposed to a sub-lethal concentration of silver nanoparticles with and without orange and banana peels water treatment for 24, 48, and 96 h. The adsorption of AgNPs on both peels was recognized by scanning electron microscopic, energy dispersive X-ray spectroscopy, and laser ablation imaging. The % of DNA damage in liver and muscle tissues (comet assay) showed significant elevations in all studied groups with the maximum level in liver tissues after 24 h. DNA damage was markedly decreased after 48, and 96 h signifying the presence of an effective repairing mechanism. Micronucleus and nine nuclear anomalies were recorded in the peripheral blood cells. All anomalies were observed in all studied groups with a maximum induction rate after 96 h. of exposure. Based on the % of DNA damage and the frequencies of nuclear anomalies, water treatment with orange and banana peel succeeded to reduce AgNPs-induced genotoxic damage.
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Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Cíclidos
/
Nanopartículas del Metal
Límite:
Animals
Idioma:
En
Revista:
Bull Environ Contam Toxicol
Año:
2022
Tipo del documento:
Article
País de afiliación:
Egipto