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An end-to-end automated platform process for high-throughput engineering of next-generation multi-specific antibody therapeutics.
Furtmann, Norbert; Schneider, Marion; Spindler, Nadja; Steinmann, Bjoern; Li, Ziyu; Focken, Ingo; Meyer, Joachim; Dimova, Dilyana; Kroll, Katja; Leuschner, Wulf Dirk; Debeaumont, Audrey; Mathieu, Magali; Lange, Christian; Dittrich, Werner; Kruip, Jochen; Schmidt, Thorsten; Birkenfeld, Joerg.
Afiliación
  • Furtmann N; R&D Large Molecules Research Platform Germany, Sanofi-Aventis Deutschland GmbH, Industriepark Höchst, Frankfurt Am Main, Germany.
  • Schneider M; R&D Large Molecules Research Platform Germany, Sanofi-Aventis Deutschland GmbH, Industriepark Höchst, Frankfurt Am Main, Germany.
  • Spindler N; R&D Large Molecules Research Platform Germany, Sanofi-Aventis Deutschland GmbH, Industriepark Höchst, Frankfurt Am Main, Germany.
  • Steinmann B; R&D Large Molecules Research Platform Germany, Sanofi-Aventis Deutschland GmbH, Industriepark Höchst, Frankfurt Am Main, Germany.
  • Li Z; R&D Integrated Drug Discovery Germany, Sanofi-Aventis Deutschland GmbH, Industriepark Höchst, Frankfurt Am Main, Germany.
  • Focken I; R&D Large Molecules Research Platform Germany, Sanofi-Aventis Deutschland GmbH, Industriepark Höchst, Frankfurt Am Main, Germany.
  • Meyer J; Digital R&D, Sanofi-Aventis Deutschland GmbH, Industriepark Höchst, Frankfurt Am Main, Germany.
  • Dimova D; R&D Large Molecules Research Platform Germany, Sanofi-Aventis Deutschland GmbH, Industriepark Höchst, Frankfurt Am Main, Germany.
  • Kroll K; R&D Large Molecules Research Platform Germany, Sanofi-Aventis Deutschland GmbH, Industriepark Höchst, Frankfurt Am Main, Germany.
  • Leuschner WD; R&D Large Molecules Research Platform Germany, Sanofi-Aventis Deutschland GmbH, Industriepark Höchst, Frankfurt Am Main, Germany.
  • Debeaumont A; R&D Large Molecules Research Platform Germany, Sanofi-Aventis Deutschland GmbH, Industriepark Höchst, Frankfurt Am Main, Germany.
  • Mathieu M; R&D Integrated Drug Discovery France, Sanofi, Vitry Sur Seine Cedex, France.
  • Lange C; R&D Large Molecules Research Platform Germany, Sanofi-Aventis Deutschland GmbH, Industriepark Höchst, Frankfurt Am Main, Germany.
  • Dittrich W; R&D Large Molecules Research Platform Germany, Sanofi-Aventis Deutschland GmbH, Industriepark Höchst, Frankfurt Am Main, Germany.
  • Kruip J; IA Specialty Care Digital Innovation Biologics, Sanofi-Aventis Deutschland GmbH, Frankfurt Am Main, Germany.
  • Schmidt T; R&D Large Molecules Research Platform Germany, Sanofi-Aventis Deutschland GmbH, Industriepark Höchst, Frankfurt Am Main, Germany.
  • Birkenfeld J; R&D Large Molecules Research Platform Germany, Sanofi-Aventis Deutschland GmbH, Industriepark Höchst, Frankfurt Am Main, Germany.
MAbs ; 13(1): 1955433, 2021.
Article en En | MEDLINE | ID: mdl-34382900
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Ingeniería de Proteínas / Biblioteca de Genes / Anticuerpos Biespecíficos / Automatización de Laboratorios / Anticuerpos Monoclonales Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: MAbs Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Alemania
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Ingeniería de Proteínas / Biblioteca de Genes / Anticuerpos Biespecíficos / Automatización de Laboratorios / Anticuerpos Monoclonales Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: MAbs Asunto de la revista: ALERGIA E IMUNOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Alemania