A viral insulin-like peptide is a natural competitive antagonist of the human IGF-1 receptor.

Zhang, Fa; Altindis, Emrah; Kahn, C Ronald; DiMarchi, Richard D; Gelfanov, Vasily

Zhang, Fa; Altindis, Emrah; Kahn, C Ronald; DiMarchi, Richard D; Gelfanov, Vasily.

Afiliación

Zhang F; Department of Chemistry, Indiana University, Bloomington, IN, 47405, USA.
Altindis E; Boston College Biology Department, Chestnut Hill, MA, 02467, USA.
Kahn CR; Joslin Diabetes Center, Harvard Medical School, Boston, MA, 02215, USA.
DiMarchi RD; Department of Chemistry, Indiana University, Bloomington, IN, 47405, USA. Electronic address: RDiMarch@indiana.edu.
Gelfanov V; Novo Nordisk Research Center, 5225 Exploration Drive, Indianapolis, IN, 46241, USA.

Mol Metab ; 53: 101316, 2021 11.

Article en En | MEDLINE | ID: mdl-34400347

Asunto(s)

Iridoviridae/química; Neuropéptidos/farmacología; Receptor IGF Tipo 1/antagonistas & inhibidores; Humanos; Neuropéptidos/química; Receptor IGF Tipo 1/metabolismo

Palabras clave

IGF-1; Insulin; Insulin-like growth factor 1; Peptide synthesis; Receptor antagonism; Virus-derived peptides

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neuropéptidos / Receptor IGF Tipo 1 / Iridoviridae Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Mol Metab Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos

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