Targeting impaired adult hippocampal neurogenesis in ageing by leveraging intrinsic mechanisms regulating Neural Stem Cell activity.

Gillotin, Sébastien; Sahni, Vishal; Lepko, Tjasa; Hanspal, Maya A; Swartz, Jina E; Alexopoulou, Zoi; Marshall, Fiona H

Gillotin, Sébastien; Sahni, Vishal; Lepko, Tjasa; Hanspal, Maya A; Swartz, Jina E; Alexopoulou, Zoi; Marshall, Fiona H.

Afiliación

Gillotin S; MSD, London Bioscience Innovation Centre, 2 Royal College Street, London, NW1 0NH, UK. Electronic address: sebastien.gillotin@msd.com.
Sahni V; MSD, London Bioscience Innovation Centre, 2 Royal College Street, London, NW1 0NH, UK.
Lepko T; MSD, London Bioscience Innovation Centre, 2 Royal College Street, London, NW1 0NH, UK.
Hanspal MA; MSD, London Bioscience Innovation Centre, 2 Royal College Street, London, NW1 0NH, UK.
Swartz JE; MSD, 2 Pancras Square, London, N1C 4AG, UK.
Alexopoulou Z; MSD, 2 Pancras Square, London, N1C 4AG, UK.
Marshall FH; MSD, London Bioscience Innovation Centre, 2 Royal College Street, London, NW1 0NH, UK.

Ageing Res Rev ; 71: 101447, 2021 11.

Article en En | MEDLINE | ID: mdl-34403830

Asunto(s)

Células-Madre Neurales; Neurogénesis; Envejecimiento; Animales; Hipocampo; Humanos; Neuronas

Palabras clave

Adult neurogenesis; Diseases of ageing; Hippocampus; Metabolism; Neural stem cells; Proteostasis

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neurogénesis / Células-Madre Neurales Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Ageing Res Rev Asunto de la revista: GERIATRIA Año: 2021 Tipo del documento: Article

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