Evaluation of single-use tangential flow filtration technology for purification of activated polysaccharides used in conjugate vaccine manufacturing.

Motevalian, Seyed Pouria; Steen, Jonathan; De Leon, Janine; Sriskanda, Verl; Carino, Ivette; Prashad, Amar S; Carrillo Conde, Brenda; Arve, Bo

Motevalian, Seyed Pouria; Steen, Jonathan; De Leon, Janine; Sriskanda, Verl; Carino, Ivette; Prashad, Amar S; Carrillo Conde, Brenda; Arve, Bo.

Afiliación

Motevalian SP; Bioprocess Research and Development, Pfizer Inc., Andover, Massachusetts, USA.
Steen J; Ultrafiltration Research and Development, MilliporeSigma, Bedford, Massachusetts, USA.
De Leon J; Bioprocess Research and Development, Pfizer Inc., Andover, Massachusetts, USA.
Sriskanda V; Analytical Research and Development, Pfizer Inc., Andover, Massachusetts, USA.
Carino I; Bioprocess Research and Development, Pfizer Inc., Andover, Massachusetts, USA.
Prashad AS; Bioprocess Research and Development, Pfizer Inc., Andover, Massachusetts, USA.
Carrillo Conde B; Bioprocess Research and Development, Pfizer Inc., Chesterfield, Missouri, USA.
Arve B; Bioprocess Research and Development, Pfizer Inc., Chesterfield, Missouri, USA.

Biotechnol Prog ; 37(6): e3204, 2021 11.

Article en En | MEDLINE | ID: mdl-34459567

Asunto(s)

Filtración/métodos; Polisacáridos; Vacunas Conjugadas/química; Biotecnología/métodos; Polisacáridos/química; Polisacáridos/aislamiento & purificación; Polisacáridos/metabolismo

Palabras clave

TFF; scale up; single use; vaccines

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Polisacáridos / Vacunas Conjugadas / Filtración Idioma: En Revista: Biotechnol Prog Asunto de la revista: BIOTECNOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos

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