Inhibition of Noncanonical Ca<sup>2+</sup> Oscillation/Calcineurin/GSK-3ß Pathway Contributes to Anti-Inflammatory Effect of Sigma-1 Receptor Activation.

Gao, Tianyu; Gao, Ce; Liu, Zhidong; Wang, Yun; Jia, Xiaoxia; Tian, Hao; Lu, Qian; Guo, Lin

Inhibition of Noncanonical Ca²⁺ Oscillation/Calcineurin/GSK-3ß Pathway Contributes to Anti-Inflammatory Effect of Sigma-1 Receptor Activation.

Gao, Tianyu; Gao, Ce; Liu, Zhidong; Wang, Yun; Jia, Xiaoxia; Tian, Hao; Lu, Qian; Guo, Lin.

Afiliación

Gao T; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, 221000, Jiangsu Province, China.
Gao C; Department of Pharmacy, The Affiliated Hospital of Xuzhou Medical University, 99 West Huai-hai Road, Xuzhou, 221004, Jiangsu Province, China.
Liu Z; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, 221000, Jiangsu Province, China.
Wang Y; Department of Pharmacy, The Affiliated Hospital of Xuzhou Medical University, 99 West Huai-hai Road, Xuzhou, 221004, Jiangsu Province, China.
Jia X; Department of Pharmacy, The Affiliated Hospital of Xuzhou Medical University, 99 West Huai-hai Road, Xuzhou, 221004, Jiangsu Province, China.
Tian H; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, 221000, Jiangsu Province, China.
Lu Q; Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, 209 Tongshan Road, Xuzhou, 221000, Jiangsu Province, China.
Guo L; Agro-Products Processing Research Institute, Yunnan Academy of Agricultural Sciences, 2238 Beijing Road, Kunming, 650000, Yunnan Province, China.

Neurochem Res ; 47(2): 264-278, 2022 Feb.

Article en En | MEDLINE | ID: mdl-34468932

Asunto(s)

Calcineurina; Microglía; Antiinflamatorios/farmacología; Calcineurina/metabolismo; Línea Celular; Glucógeno Sintasa Quinasa 3 beta/metabolismo; Lipopolisacáridos/farmacología; Microglía/metabolismo; FN-kappa B/metabolismo; Óxido Nítrico/metabolismo; Óxido Nítrico Sintasa de Tipo II/metabolismo; Receptores sigma; Factor de Necrosis Tumoral alfa/metabolismo; Receptor Sigma-1

Palabras clave

Ca2+ oscillation; Calcineurin; Glycogen synthase kinase-3 beta; Neuroinflammation; Sigma-1 receptor

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Microglía / Calcineurina Tipo de estudio: Prognostic_studies Idioma: En Revista: Neurochem Res Año: 2022 Tipo del documento: Article País de afiliación: China

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