Association between pathogenic germline mutations in BRCA2 and ATM and tumor-infiltrating lymphocytes in primary prostate cancer.

Kaur, Harsimar B; Vidotto, Thiago; Mendes, Adrianna A; Salles, Daniela C; Isaacs, William B; Antonarakis, Emmanuel S; Lotan, Tamara L

Kaur, Harsimar B; Vidotto, Thiago; Mendes, Adrianna A; Salles, Daniela C; Isaacs, William B; Antonarakis, Emmanuel S; Lotan, Tamara L.

Afiliación

Kaur HB; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Vidotto T; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Mendes AA; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Salles DC; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Isaacs WB; Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Antonarakis ES; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, CRB2, Room 316, 1550 Orleans Street, Baltimore, MD, 21287, USA.
Lotan TL; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. tlotan1@jhmi.edu.

Cancer Immunol Immunother ; 71(4): 943-951, 2022 Apr.

Article en En | MEDLINE | ID: mdl-34533610

Asunto(s)

Mutación de Línea Germinal; Neoplasias de la Próstata; Proteínas de la Ataxia Telangiectasia Mutada/genética; Proteína BRCA2/genética; Biomarcadores de Tumor/genética; Genes BRCA2; Humanos; Linfocitos Infiltrantes de Tumor; Masculino; Neoplasias de la Próstata/genética

Palabras clave

ATM; BRCA2; CD8; FOXP3; PD-L1; Prostatic adenocarcinoma; T-cells; Tumor-infiltrating lymphocytes

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias de la Próstata / Mutación de Línea Germinal Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Humans / Male Idioma: En Revista: Cancer Immunol Immunother Asunto de la revista: ALERGIA E IMUNOLOGIA / NEOPLASIAS / TERAPEUTICA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos

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