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Thienylpiperidine Donor NIR Xanthene-Based Dye for Photoacoustic Imaging.
Rathnamalala, Chathuranga S L; Pino, Nicholas W; Herring, Bailey S; Hooper, Mattea; Gwaltney, Steven R; Chan, Jefferson; Scott, Colleen N.
Afiliación
  • Rathnamalala CSL; Department of Chemistry, Mississippi State University, Mississippi State, Mississippi 39762, United States.
  • Pino NW; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.
  • Herring BS; Department of Chemistry, Mississippi State University, Mississippi State, Mississippi 39762, United States.
  • Hooper M; Department of Chemistry, Mississippi State University, Mississippi State, Mississippi 39762, United States.
  • Gwaltney SR; Department of Chemistry, Mississippi State University, Mississippi State, Mississippi 39762, United States.
  • Chan J; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.
  • Scott CN; Department of Chemistry, Mississippi State University, Mississippi State, Mississippi 39762, United States.
Org Lett ; 23(19): 7640-7644, 2021 10 01.
Article en En | MEDLINE | ID: mdl-34550707
ABSTRACT
Few xanthene-based near-infrared (NIR) photoacoustic (PA) dyes with absorbance >800 nm exist. As accessibility to these dyes requires long and tedious synthetic steps, we designed a NIR dye (XanthCR-880) with thienylpiperidine donors and a xanthene acceptor that is accessible in 3-4 synthetic steps. The dye boasts a strong PA signal at 880 nm with good biological compatibility and photostability, yields multiplexed imaging with an aza-BODIPY reference dye, and is detected at a depth of 4 cm.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Xantenos / Benzopiranos / Compuestos de Boro / Colorantes Fluorescentes Idioma: En Revista: Org Lett Asunto de la revista: BIOQUIMICA Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Xantenos / Benzopiranos / Compuestos de Boro / Colorantes Fluorescentes Idioma: En Revista: Org Lett Asunto de la revista: BIOQUIMICA Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos