The return of chloroquine-sensitive Plasmodium falciparum parasites in Jazan region, southwestern Saudi Arabia over a decade after the adoption of artemisinin-based combination therapy: analysis of genetic mutations in the pfcrt gene.

Madkhali, Aymen M; Abdulhaq, Ahmed A; Atroosh, Wahib M; Ghzwani, Ahmad Hassn; Zain, Khalid Ammash; Ghailan, Khalid Y; Hamali, Hassan A; Mobarki, Abdullah A; Eisa, Zaki M; Lau, Yee-Ling; Al-Mekhlafi, Hesham M

Madkhali, Aymen M; Abdulhaq, Ahmed A; Atroosh, Wahib M; Ghzwani, Ahmad Hassn; Zain, Khalid Ammash; Ghailan, Khalid Y; Hamali, Hassan A; Mobarki, Abdullah A; Eisa, Zaki M; Lau, Yee-Ling; Al-Mekhlafi, Hesham M.

Afiliación

Madkhali AM; Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, Jazan University, Jazan, Kingdom of Saudi Arabia.
Abdulhaq AA; Medical Research Centre, Jazan University, Jazan, Kingdom of Saudi Arabia.
Atroosh WM; Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, Jazan University, Jazan, Kingdom of Saudi Arabia.
Ghzwani AH; Department of Parasitology, Faculty of Medicine, University of Malaya, 50603, Kuala Lumpur, Malaysia.
Zain KA; Department of Microbiology and Parasitology, Faculty of Medicine and Health Sciences, University of Aden, Aden, Yemen.
Ghailan KY; Medical Research Centre, Jazan University, Jazan, Kingdom of Saudi Arabia.
Hamali HA; Medical Research Centre, Jazan University, Jazan, Kingdom of Saudi Arabia.
Mobarki AA; Faculty of Public Health and Tropical Medicine, Jazan University, Jazan, Kingdom of Saudi Arabia.
Eisa ZM; Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, Jazan University, Jazan, Kingdom of Saudi Arabia.
Lau YL; Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, Jazan University, Jazan, Kingdom of Saudi Arabia.
Al-Mekhlafi HM; Saudi Centre for Disease Prevention and Control, Ministry of Health, Jazan, Kingdom of Saudi Arabia.

Parasitol Res ; 120(11): 3771-3781, 2021 Nov.

Article en En | MEDLINE | ID: mdl-34561749

Asunto(s)

Antimaláricos; Artemisininas; Malaria Falciparum; Parásitos; Animales; Antimaláricos/farmacología; Antimaláricos/uso terapéutico; Artemisininas/uso terapéutico; Cloroquina/farmacología; Cloroquina/uso terapéutico; Resistencia a Medicamentos/genética; Humanos; Malaria Falciparum/tratamiento farmacológico; Malaria Falciparum/epidemiología; Mutación; Plasmodium falciparum/genética; Proteínas Protozoarias/genética; Arabia Saudita

Palabras clave

Chloroquine; Drug resistance; Infectious diseases; Malaria; Pfcrt; Plasmodium falciparum; Saudi Arabia

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Parásitos / Malaria Falciparum / Artemisininas / Antimaláricos Tipo de estudio: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Límite: Animals / Humans País/Región como asunto: Asia Idioma: En Revista: Parasitol Res Asunto de la revista: PARASITOLOGIA Año: 2021 Tipo del documento: Article

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