Glaucocalyxin B inhibits cartilage inflammatory injury in rheumatoid arthritis by regulating M1 polarization of synovial macrophages through NF-&#954;B pathway.

Han, Chenyang; Yang, Yi; Sheng, Yongjia; Wang, Jin; Zhou, Xiaohong; Li, Wenyan; Guo, Li; Zhang, Caiqun; Ye, Qiao

Glaucocalyxin B inhibits cartilage inflammatory injury in rheumatoid arthritis by regulating M1 polarization of synovial macrophages through NF-κB pathway.

Han, Chenyang; Yang, Yi; Sheng, Yongjia; Wang, Jin; Zhou, Xiaohong; Li, Wenyan; Guo, Li; Zhang, Caiqun; Ye, Qiao.

Afiliación

Han C; Department of Pharmacy, The Second Affiliated Hospital of Jiaxing University, Zhejiang, China.
Yang Y; Department of Pharmacy, The Second Affiliated Hospital of Jiaxing University, Zhejiang, China.
Sheng Y; Department of Pharmacy, The Second Affiliated Hospital of Jiaxing University, Zhejiang, China.
Wang J; Department of Pharmacy, The Second Affiliated Hospital of Jiaxing University, Zhejiang, China.
Zhou X; Department of Center Laboratory, The Second Affiliated Hospital of Jiaxing University, Zhejiang, China.
Li W; Department of Pharmacy, The Second Affiliated Hospital of Jiaxing University, Zhejiang, China.
Guo L; Department of Center Laboratory, The Second Affiliated Hospital of Jiaxing University, Zhejiang, China.
Zhang C; Department of Pharmacy, The Second Affiliated Hospital of Jiaxing University, Zhejiang, China.
Ye Q; Department of Rheumatology and Immunology, The Second Affiliated Hospital of Jiaxing University, Zhejiang, China.

Aging (Albany NY) ; 13(18): 22544-22555, 2021 09 27.

Article en En | MEDLINE | ID: mdl-34580236

Asunto(s)

Antiinflamatorios/farmacología; Artritis Reumatoide/metabolismo; Cartílago; Diterpenos de Tipo Kaurano/farmacología; Inflamación/metabolismo; FN-kappa B/metabolismo; Membrana Sinovial/efectos de los fármacos; Animales; Artritis Reumatoide/inmunología; Macrófagos/efectos de los fármacos; Ratones; Transducción de Señal/efectos de los fármacos; Factor de Necrosis Tumoral alfa/metabolismo

Palabras clave

Glaucocalyxin B; NF-κB; cartilage injury; macrophages; rheumatoid arthritis

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Artritis Reumatoide / Membrana Sinovial / Cartílago / FN-kappa B / Diterpenos de Tipo Kaurano / Inflamación / Antiinflamatorios Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Aging (Albany NY) Asunto de la revista: GERIATRIA Año: 2021 Tipo del documento: Article País de afiliación: China

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