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The extracellular matrix glycoprotein ADAMTSL2 is increased in heart failure and inhibits TGFß signalling in cardiac fibroblasts.
Rypdal, Karoline B; Erusappan, Pugazendhi M; Melleby, A Olav; Seifert, Deborah E; Palmero, Sheryl; Strand, Mari E; Tønnessen, Theis; Dahl, Christen P; Almaas, Vibeke; Hubmacher, Dirk; Apte, Suneel S; Christensen, Geir; Lunde, Ida G.
Afiliación
  • Rypdal KB; Institute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Building 7, 4th floor, Kirkeveien 166, 0407, Oslo, Norway.
  • Erusappan PM; KG Jebsen Cardiac Research Center and Center for Heart Failure Research, University of Oslo, Oslo, Norway.
  • Melleby AO; Institute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Building 7, 4th floor, Kirkeveien 166, 0407, Oslo, Norway.
  • Seifert DE; KG Jebsen Cardiac Research Center and Center for Heart Failure Research, University of Oslo, Oslo, Norway.
  • Palmero S; Institute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Building 7, 4th floor, Kirkeveien 166, 0407, Oslo, Norway.
  • Strand ME; KG Jebsen Cardiac Research Center and Center for Heart Failure Research, University of Oslo, Oslo, Norway.
  • Tønnessen T; Section of Physiology, Department of Molecular Medicine, Institute for Basic Medical Sciences, University of Oslo, Oslo, Norway.
  • Dahl CP; Department of Biomedical Engineering, Cleveland Clinic Lerner Institute, Cleveland, OH, USA.
  • Almaas V; Institute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Building 7, 4th floor, Kirkeveien 166, 0407, Oslo, Norway.
  • Hubmacher D; KG Jebsen Cardiac Research Center and Center for Heart Failure Research, University of Oslo, Oslo, Norway.
  • Apte SS; Institute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Building 7, 4th floor, Kirkeveien 166, 0407, Oslo, Norway.
  • Christensen G; KG Jebsen Cardiac Research Center and Center for Heart Failure Research, University of Oslo, Oslo, Norway.
  • Lunde IG; Institute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Building 7, 4th floor, Kirkeveien 166, 0407, Oslo, Norway.
Sci Rep ; 11(1): 19757, 2021 10 05.
Article en En | MEDLINE | ID: mdl-34611183
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Transducción de Señal / Proteínas de la Matriz Extracelular / Matriz Extracelular / Fibroblastos / Proteínas ADAMTS / Insuficiencia Cardíaca Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Sci Rep Año: 2021 Tipo del documento: Article País de afiliación: Noruega
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Transducción de Señal / Proteínas de la Matriz Extracelular / Matriz Extracelular / Fibroblastos / Proteínas ADAMTS / Insuficiencia Cardíaca Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Sci Rep Año: 2021 Tipo del documento: Article País de afiliación: Noruega