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1,2,4-Triazole-3-thione compounds with a 4-ethyl alkyl/aryl sulfide substituent are broad-spectrum metallo-ß-lactamase inhibitors with re-sensitization activity.
Legru, Alice; Verdirosa, Federica; Hernandez, Jean-François; Tassone, Giusy; Sannio, Filomena; Benvenuti, Manuela; Conde, Pierre-Alexis; Bossis, Guillaume; Thomas, Caitlyn A; Crowder, Michael W; Dillenberger, Melissa; Becker, Katja; Pozzi, Cecilia; Mangani, Stefano; Docquier, Jean-Denis; Gavara, Laurent.
Afiliación
  • Legru A; IBMM, CNRS, Univ Montpellier, ENSCM, Montpellier, France.
  • Verdirosa F; Dipartimento di Biotecnologie Mediche, Università di Siena, 53100, Siena, Italy.
  • Hernandez JF; IBMM, CNRS, Univ Montpellier, ENSCM, Montpellier, France. Electronic address: jean-francois.hernandez@umontpellier.fr.
  • Tassone G; Dipartimento di Biotecnologie, Chimica e Pharmacia, Università di Siena, 53100, Siena, Italy.
  • Sannio F; Dipartimento di Biotecnologie Mediche, Università di Siena, 53100, Siena, Italy.
  • Benvenuti M; Dipartimento di Biotecnologie, Chimica e Pharmacia, Università di Siena, 53100, Siena, Italy.
  • Conde PA; IBMM, CNRS, Univ Montpellier, ENSCM, Montpellier, France.
  • Bossis G; IGMM, Univ Montpellier, CNRS, Montpellier, France.
  • Thomas CA; Department of Chemistry and Biochemistry, Miami University, Oxford, OH, USA.
  • Crowder MW; Department of Chemistry and Biochemistry, Miami University, Oxford, OH, USA.
  • Dillenberger M; Chair of Biochemistry and Molecular Biology, Interdisciplinary Research Center, Justus Liebig University, D-35392, Giessen, Germany.
  • Becker K; Chair of Biochemistry and Molecular Biology, Interdisciplinary Research Center, Justus Liebig University, D-35392, Giessen, Germany.
  • Pozzi C; Dipartimento di Biotecnologie, Chimica e Pharmacia, Università di Siena, 53100, Siena, Italy.
  • Mangani S; Dipartimento di Biotecnologie, Chimica e Pharmacia, Università di Siena, 53100, Siena, Italy.
  • Docquier JD; Dipartimento di Biotecnologie Mediche, Università di Siena, 53100, Siena, Italy; Centre d'Ingénierie des Protéines-InBioS, Université de Liège, B-4000, Liège, Belgium. Electronic address: jddocquier@unisi.it.
  • Gavara L; IBMM, CNRS, Univ Montpellier, ENSCM, Montpellier, France. Electronic address: laurent.gavara@umontpellier.fr.
Eur J Med Chem ; 226: 113873, 2021 Dec 15.
Article en En | MEDLINE | ID: mdl-34626878
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Sulfuros / Tionas / Triazoles / Beta-Lactamasas / Inhibidores de beta-Lactamasas Límite: Humans Idioma: En Revista: Eur J Med Chem Año: 2021 Tipo del documento: Article País de afiliación: Francia
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Sulfuros / Tionas / Triazoles / Beta-Lactamasas / Inhibidores de beta-Lactamasas Límite: Humans Idioma: En Revista: Eur J Med Chem Año: 2021 Tipo del documento: Article País de afiliación: Francia