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Chloropyridinyl Esters of Nonsteroidal Anti-Inflammatory Agents and Related Derivatives as Potent SARS-CoV-2 3CL Protease Inhibitors.
Ghosh, Arun K; Shahabi, Dana; Yadav, Monika; Kovela, Satish; Anson, Brandon J; Lendy, Emma K; Bonham, Connie; Sirohi, Devika; Brito-Sierra, Carlos A; Hattori, Shin-Ichiro; Kuhn, Richard; Mitsuya, Hiroaki; Mesecar, Andrew D.
Afiliación
  • Ghosh AK; Department of Chemistry; Department of Medicinal Chemistry, Purdue University, West Lafayette, IN 47907, USA.
  • Shahabi D; Department of Chemistry; Department of Medicinal Chemistry, Purdue University, West Lafayette, IN 47907, USA.
  • Yadav M; Department of Chemistry; Department of Medicinal Chemistry, Purdue University, West Lafayette, IN 47907, USA.
  • Kovela S; Department of Chemistry; Department of Medicinal Chemistry, Purdue University, West Lafayette, IN 47907, USA.
  • Anson BJ; Department of Biological Sciences, Purdue University, West Lafayette, IN 47907, USA.
  • Lendy EK; Department of Biochemistry, Purdue University, West Lafayette, IN 47907, USA.
  • Bonham C; Bindley Bioscience Center, Purdue University, West Lafayette, IN 47907, USA.
  • Sirohi D; Department of Biological Sciences, Purdue University, West Lafayette, IN 47907, USA.
  • Brito-Sierra CA; Purdue Institute of Inflammation, Immunology and Infectious Disease, Purdue University, West Lafayette, IN 47907, USA.
  • Hattori SI; Department of Biological Sciences, Purdue University, West Lafayette, IN 47907, USA.
  • Kuhn R; Purdue Institute of Inflammation, Immunology and Infectious Disease, Purdue University, West Lafayette, IN 47907, USA.
  • Mitsuya H; Departments of Hematology and Infectious Diseases, Kumamoto University School of Medicine, Kumamoto 860-8556, Japan.
  • Mesecar AD; Department of Refractory Viral Infections, National Center for Global Health and Medicine Research Institute, Tokyo 162-8655, Japan.
Molecules ; 26(19)2021 Sep 24.
Article en En | MEDLINE | ID: mdl-34641337
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Inhibidores de Proteasas / Antiinflamatorios no Esteroideos / Proteasas 3C de Coronavirus / SARS-CoV-2 / Tratamiento Farmacológico de COVID-19 Límite: Animals / Humans Idioma: En Revista: Molecules Asunto de la revista: BIOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Inhibidores de Proteasas / Antiinflamatorios no Esteroideos / Proteasas 3C de Coronavirus / SARS-CoV-2 / Tratamiento Farmacológico de COVID-19 Límite: Animals / Humans Idioma: En Revista: Molecules Asunto de la revista: BIOLOGIA Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos