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Discovery of novel triazole compounds as selective IL-1ß releasement inhibitors.
Mu, Ruixu; Zhou, Yongting; Chen, Leyuan; Wei, Huiqiang; Yu, Jingcheng; Gou, Wenfeng; Ye, Caiying; Hou, Wenbin; Li, Yiliang; Zhu, Lei.
Afiliación
  • Mu R; Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Peking Union Medical College & Chinese Academy of Medical Sciences, Tianjin 300192, China.
  • Zhou Y; Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing 100100, China.
  • Chen L; Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Peking Union Medical College & Chinese Academy of Medical Sciences, Tianjin 300192, China.
  • Wei H; Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Peking Union Medical College & Chinese Academy of Medical Sciences, Tianjin 300192, China.
  • Yu J; Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China.
  • Gou W; Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Peking Union Medical College & Chinese Academy of Medical Sciences, Tianjin 300192, China.
  • Ye C; Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing 100100, China.
  • Hou W; Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Peking Union Medical College & Chinese Academy of Medical Sciences, Tianjin 300192, China. Electronic address: houwenbin@irm-cams.ac.cn.
  • Li Y; Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Peking Union Medical College & Chinese Academy of Medical Sciences, Tianjin 300192, China. Electronic address: liyiliang@irm-cams.ac.cn.
  • Zhu L; Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College, Beijing 100100, China. Electronic address: leizhu2004@126.com.
Bioorg Med Chem Lett ; 53: 128415, 2021 12 01.
Article en En | MEDLINE | ID: mdl-34662706
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Triazoles / Interleucina-1beta / Descubrimiento de Drogas Límite: Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2021 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Triazoles / Interleucina-1beta / Descubrimiento de Drogas Límite: Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2021 Tipo del documento: Article País de afiliación: China