Anti-Food Allergic Alkaloids from the Lotus Seed Pot.
Chem Biodivers
; 18(12): e2100770, 2021 Dec.
Article
en En
| MEDLINE
| ID: mdl-34664390
ABSTRACT
Lotus seed pod (LSP) has been used as traditional herbal cuisine to modulate immunity. From the AcOEt-soluble extract of LSP, one new aporphine alkaloid, N-[2-(2H-phenanthro[3,4-d][1,3]dioxol-5-yl)ethyl]acetamide (nelunucine A, 1) was obtained along with 19 known ones. Their structures were established by detailed analysis of the 1D-, 2D-NMR, and HR-ESI-MS data. N-Nornuciferine (9) and lirinidine (10) showed potent inâ
vitro anti-food allergic activity with IC50 values of 40.0 and 55.4â
µM, respectively, compared to 91.4â
µM for loratadine, the positive control.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Semillas
/
Antialérgicos
/
Alcaloides
/
Lotus
/
Hipersensibilidad a los Alimentos
Límite:
Animals
Idioma:
En
Revista:
Chem Biodivers
Asunto de la revista:
BIOQUIMICA
/
QUIMICA
Año:
2021
Tipo del documento:
Article
País de afiliación:
China