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Molecular modelling of the FOXO4-TP53 interaction to design senolytic peptides for the elimination of senescent cancer cells.
Le, Hillary H; Cinaroglu, Suleyman S; Manalo, Elise C; Ors, Aysegul; Gomes, Michelle M; Duan Sahbaz, Burcin; Bonic, Karla; Origel Marmolejo, Carlos A; Quentel, Arnaud; Plaut, Justin S; Kawashima, Taryn E; Ozdemir, E Sila; Malhotra, Sanjay V; Ahiska, Yavuz; Sezerman, Ugur; Bayram Akcapinar, Gunseli; Saldivar, Joshua C; Timucin, Emel; Fischer, Jared M.
Afiliación
  • Le HH; Cancer Early Detection Advanced Research Center, Knight Cancer Institute, Oregon Health & Science University, USA.
  • Cinaroglu SS; Institute of Health Sciences, Acibadem Mehmet Ali Aydinlar University, Atasehir Istanbul 34752, Turkey; Eternans Ltd., UK.
  • Manalo EC; Cancer Early Detection Advanced Research Center, Knight Cancer Institute, Oregon Health & Science University, USA.
  • Ors A; Cancer Early Detection Advanced Research Center, Knight Cancer Institute, Oregon Health & Science University, USA.
  • Gomes MM; Cancer Early Detection Advanced Research Center, Knight Cancer Institute, Oregon Health & Science University, USA.
  • Duan Sahbaz B; Eternans Ltd., UK.
  • Bonic K; Cancer Early Detection Advanced Research Center, Knight Cancer Institute, Oregon Health & Science University, USA.
  • Origel Marmolejo CA; Cancer Early Detection Advanced Research Center, Knight Cancer Institute, Oregon Health & Science University, USA.
  • Quentel A; Cancer Early Detection Advanced Research Center, Knight Cancer Institute, Oregon Health & Science University, USA.
  • Plaut JS; Cancer Early Detection Advanced Research Center, Knight Cancer Institute, Oregon Health & Science University, USA; Dept of Bioengineering, University of California San Diego, USA.
  • Kawashima TE; Cancer Early Detection Advanced Research Center, Knight Cancer Institute, Oregon Health & Science University, USA.
  • Ozdemir ES; Cancer Early Detection Advanced Research Center, Knight Cancer Institute, Oregon Health & Science University, USA.
  • Malhotra SV; Cancer Early Detection Advanced Research Center, Knight Cancer Institute, Oregon Health & Science University, USA; Dept of Cell, Developmental and Cancer Biology, Oregon Health & Science University, USA.
  • Ahiska Y; Eternans Ltd., UK.
  • Sezerman U; Eternans Ltd., UK; School of Medicine, Acibadem Mehmet Ali Aydinlar University, Atasehir Istanbul 34752, Turkey.
  • Bayram Akcapinar G; Institute of Health Sciences, Acibadem Mehmet Ali Aydinlar University, Atasehir Istanbul 34752, Turkey; Eternans Ltd., UK.
  • Saldivar JC; Cancer Early Detection Advanced Research Center, Knight Cancer Institute, Oregon Health & Science University, USA; Division of Oncological Sciences, Knight Cancer Institute, Oregon Health & Science University, USA.
  • Timucin E; Eternans Ltd., UK; School of Medicine, Acibadem Mehmet Ali Aydinlar University, Atasehir Istanbul 34752, Turkey.
  • Fischer JM; Cancer Early Detection Advanced Research Center, Knight Cancer Institute, Oregon Health & Science University, USA; Dept of Molecular and Medical Genetics, Oregon Health & Science University, USA. Electronic address: fischerj@ohsu.edu.
EBioMedicine ; 73: 103646, 2021 Nov.
Article en En | MEDLINE | ID: mdl-34689087
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Péptidos / Diseño de Fármacos / Modelos Moleculares / Proteína p53 Supresora de Tumor / Proteínas de Ciclo Celular / Factores de Transcripción Forkhead / Senoterapéuticos / Antineoplásicos Tipo de estudio: Prognostic_studies / Screening_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: EBioMedicine Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Péptidos / Diseño de Fármacos / Modelos Moleculares / Proteína p53 Supresora de Tumor / Proteínas de Ciclo Celular / Factores de Transcripción Forkhead / Senoterapéuticos / Antineoplásicos Tipo de estudio: Prognostic_studies / Screening_studies Límite: Animals / Female / Humans / Male Idioma: En Revista: EBioMedicine Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos