High-dose copper activates p53-independent apoptosis through the induction of nucleolar stress in human cell lines.

Chen, Chieh-Hsin; Chou, Yi-Ting; Yang, Ya-Wen; Lo, Kai-Yin

Chen, Chieh-Hsin; Chou, Yi-Ting; Yang, Ya-Wen; Lo, Kai-Yin.

Afiliación

Chen CH; Department of Agricultural Chemistry, National Taiwan University, 1 Sec. 4, Roosevelt Road, Taipei, 10617, Taiwan.
Chou YT; Department of Agricultural Chemistry, National Taiwan University, 1 Sec. 4, Roosevelt Road, Taipei, 10617, Taiwan.
Yang YW; Department of Surgery, National Taiwan University Hospital, Taipei, Taiwan.
Lo KY; Department of Agricultural Chemistry, National Taiwan University, 1 Sec. 4, Roosevelt Road, Taipei, 10617, Taiwan. kaiyin@ntu.edu.tw.

Apoptosis ; 26(11-12): 612-627, 2021 12.

Article en En | MEDLINE | ID: mdl-34708319

Asunto(s)

Cobre; Proteína p53 Supresora de Tumor; Apoptosis; Línea Celular; Cobre/toxicidad; Humanos; Nucleofosmina; Proteína p53 Supresora de Tumor/genética

Palabras clave

Copper stress; Nucleolar stress; Protein synthesis; Ribosome biogenesis; rRNA processing

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteína p53 Supresora de Tumor / Cobre Límite: Humans Idioma: En Revista: Apoptosis Año: 2021 Tipo del documento: Article País de afiliación: Taiwán

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