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Oral prodrug of remdesivir parent GS-441524 is efficacious against SARS-CoV-2 in ferrets.
Cox, Robert M; Wolf, Josef D; Lieber, Carolin M; Sourimant, Julien; Lin, Michelle J; Babusis, Darius; DuPont, Venice; Chan, Julie; Barrett, Kim T; Lye, Diane; Kalla, Rao; Chun, Kwon; Mackman, Richard L; Ye, Chengjin; Cihlar, Tomas; Martinez-Sobrido, Luis; Greninger, Alexander L; Bilello, John P; Plemper, Richard K.
Afiliación
  • Cox RM; Center for Translational Antiviral Research, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA, USA.
  • Wolf JD; Center for Translational Antiviral Research, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA, USA.
  • Lieber CM; Center for Translational Antiviral Research, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA, USA.
  • Sourimant J; Center for Translational Antiviral Research, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA, USA.
  • Lin MJ; Virology Division, Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA.
  • Babusis D; Gilead Sciences Inc, Foster City, CA, USA.
  • DuPont V; Gilead Sciences Inc, Foster City, CA, USA.
  • Chan J; Gilead Sciences Inc, Foster City, CA, USA.
  • Barrett KT; Gilead Sciences Inc, Foster City, CA, USA.
  • Lye D; Gilead Sciences Inc, Foster City, CA, USA.
  • Kalla R; Gilead Sciences Inc, Foster City, CA, USA.
  • Chun K; Gilead Sciences Inc, Foster City, CA, USA.
  • Mackman RL; Gilead Sciences Inc, Foster City, CA, USA.
  • Ye C; Texas Biomedical Research Institute, San Antonio, TX, USA.
  • Cihlar T; Gilead Sciences Inc, Foster City, CA, USA.
  • Martinez-Sobrido L; Texas Biomedical Research Institute, San Antonio, TX, USA.
  • Greninger AL; Virology Division, Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA.
  • Bilello JP; Gilead Sciences Inc, Foster City, CA, USA.
  • Plemper RK; Center for Translational Antiviral Research, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA, USA. rplemper@gsu.edu.
Nat Commun ; 12(1): 6415, 2021 11 05.
Article en En | MEDLINE | ID: mdl-34741049
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Antivirales / Profármacos / Adenosina / SARS-CoV-2 / Tratamiento Farmacológico de COVID-19 Límite: Animals / Female / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Antivirales / Profármacos / Adenosina / SARS-CoV-2 / Tratamiento Farmacológico de COVID-19 Límite: Animals / Female / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos