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A Phase 2a randomized, single-center, double-blind, placebo-controlled study to evaluate the safety and preliminary efficacy of oral iOWH032 against cholera diarrhea in a controlled human infection model.
Erdem, Rahsan; Ambler, Gwen; Al-Ibrahim, Mohamed; Fraczek, Katarzyna; Dong, Steven D; Gast, Christopher; Mercer, Laina D; Raine, Michael; Tennant, Sharon M; Chen, Wilbur H; de Hostos, Eugenio L; Choy, Robert K M.
Afiliación
  • Erdem R; PATH, Seattle, Washington, United States of America.
  • Ambler G; PATH, Seattle, Washington, United States of America.
  • Al-Ibrahim M; Pharmaron, Baltimore, Maryland, United States of America.
  • Fraczek K; Pharmaron, Baltimore, Maryland, United States of America.
  • Dong SD; PATH, Seattle, Washington, United States of America.
  • Gast C; PATH, Seattle, Washington, United States of America.
  • Mercer LD; PATH, Seattle, Washington, United States of America.
  • Raine M; PATH, Seattle, Washington, United States of America.
  • Tennant SM; Center for Vaccine Development and Global Health, School of Medicine, University of Maryland, Baltimore, Maryland, United States of America.
  • Chen WH; Center for Vaccine Development and Global Health, School of Medicine, University of Maryland, Baltimore, Maryland, United States of America.
  • de Hostos EL; PATH, Seattle, Washington, United States of America.
  • Choy RKM; PATH, Seattle, Washington, United States of America.
PLoS Negl Trop Dis ; 15(11): e0009969, 2021 11.
Article en En | MEDLINE | ID: mdl-34793441
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Oxadiazoles / Cólera / Diarrea / Hidroxiquinolinas Tipo de estudio: Clinical_trials / Risk_factors_studies Límite: Adolescent / Adult / Female / Humans / Male Idioma: En Revista: PLoS Negl Trop Dis Asunto de la revista: MEDICINA TROPICAL Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Oxadiazoles / Cólera / Diarrea / Hidroxiquinolinas Tipo de estudio: Clinical_trials / Risk_factors_studies Límite: Adolescent / Adult / Female / Humans / Male Idioma: En Revista: PLoS Negl Trop Dis Asunto de la revista: MEDICINA TROPICAL Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos