Ad-apoptin inhibits glycolysis, migration and invasion in lung cancer cells targeting AMPK/mTOR signaling pathway.

Song, Gaojie; Fang, Jinbo; Shang, Chao; Li, Yiquan; Zhu, Yilong; Xiu, Zhiru; Sun, Lili; Jin, Ningyi; Li, Xiao

Song, Gaojie; Fang, Jinbo; Shang, Chao; Li, Yiquan; Zhu, Yilong; Xiu, Zhiru; Sun, Lili; Jin, Ningyi; Li, Xiao.

Afiliación

Song G; Medical College, Yanbian University, Yanji, China; Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun, China; Academician Workstation of Jilin Province, Changchun University of Chinese Medicine, Changchun, China.
Fang J; Academician Workstation of Jilin Province, Changchun University of Chinese Medicine, Changchun, China.
Shang C; Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun, China.
Li Y; Academician Workstation of Jilin Province, Changchun University of Chinese Medicine, Changchun, China.
Zhu Y; Academician Workstation of Jilin Province, Changchun University of Chinese Medicine, Changchun, China.
Xiu Z; Academician Workstation of Jilin Province, Changchun University of Chinese Medicine, Changchun, China.
Sun L; Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun, China; Department of Head and Neck Surgery, Tumor Hospital of Jilin Province, Changchun, China. Electronic address: linjiaxiaoya@163.com.
Jin N; Medical College, Yanbian University, Yanji, China; Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun, China; Academician Workstation of Jilin Province, Changchun University of Chinese Medicine, Changchun, China. Electronic address: ningyik@126.com.
Li X; Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Changchun, China; Academician Workstation of Jilin Province, Changchun University of Chinese Medicine, Changchun, China. Electronic address: lixiao06@mails.jlu.edu.cn.

Exp Cell Res ; 409(2): 112926, 2021 12 15.

Article en En | MEDLINE | ID: mdl-34793774

Asunto(s)

Proteínas Quinasas Activadas por AMP/metabolismo; Adenoviridae/genética; Proteínas de la Cápside/genética; Carcinoma de Pulmón de Células no Pequeñas/patología; Glucólisis; Viroterapia Oncolítica/métodos; Serina-Treonina Quinasas TOR/metabolismo; Proteínas Quinasas Activadas por AMP/genética; Animales; Apoptosis; Biomarcadores de Tumor/genética; Biomarcadores de Tumor/metabolismo; Carcinoma de Pulmón de Células no Pequeñas/genética; Carcinoma de Pulmón de Células no Pequeñas/metabolismo; Carcinoma de Pulmón de Células no Pequeñas/terapia; Ciclo Celular; Movimiento Celular; Proliferación Celular; Femenino; Regulación Neoplásica de la Expresión Génica; Humanos; Neoplasias Pulmonares/genética; Neoplasias Pulmonares/metabolismo; Neoplasias Pulmonares/patología; Neoplasias Pulmonares/terapia; Ratones; Ratones Endogámicos BALB C; Ratones Desnudos; Invasividad Neoplásica; Serina-Treonina Quinasas TOR/genética; Células Tumorales Cultivadas; Ensayos Antitumor por Modelo de Xenoinjerto

Palabras clave

AMPK/mTOR signaling; Ad-apoptin; Epithelial-mesenchymal transition; Glycolysis

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Adenoviridae / Carcinoma de Pulmón de Células no Pequeñas / Proteínas de la Cápside / Viroterapia Oncolítica / Proteínas Quinasas Activadas por AMP / Serina-Treonina Quinasas TOR / Glucólisis Límite: Animals / Female / Humans Idioma: En Revista: Exp Cell Res Año: 2021 Tipo del documento: Article País de afiliación: China

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