The challenge of targets and drug discovery using large-scale screening approaches in onco-hematology.
Therapie
; 77(2): 151-155, 2022.
Article
en En
| MEDLINE
| ID: mdl-34895756
ABSTRACT
Target identification and drug discovery roads have been widely improved over the past decades in onco-hematology. In this review, we summarize recent improvements in the use of physio-pathologically relevant models and innovative screening approaches to accelerate efficient drug development. Using acute myeloid leukemia as an example, we also discuss the main encountered pitfalls and propose alternative roads to improve the drug discovery journey in onco-hematology.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Hematología
Tipo de estudio:
Diagnostic_studies
/
Screening_studies
Límite:
Humans
Idioma:
En
Revista:
Therapie
Año:
2022
Tipo del documento:
Article
País de afiliación:
Francia