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Anti-inflammatory, but not osteoprotective, effect of the TRAF6/CD40 inhibitor 6877002 in rodent models of local and systemic osteolysis.
Marino, Silvia; Hannemann, Nicole; Bishop, Ryan T; Zeng, Feier; Carrasco, Giovana; Meurisse, Sandrine; Li, Boya; Sophocleous, Antonia; Sparatore, Anna; Baeuerle, Tobias; Vukicevic, Slobodan; Auberval, Marielle; Mollat, Patrick; Bozec, Aline; Idris, Aymen I.
Afiliación
  • Marino S; Department of Oncology and Metabolism, University of Sheffield, Medical School, Beech Hill Road, Sheffield S10 2RX, UK; Bone and Cancer Group, Edinburgh Cancer Research Centre, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, EH4 2XR, UK.
  • Hannemann N; Department of Internal Medicine, 3-Rheumatology and Immunology, Friedrich-Alexander University Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany.
  • Bishop RT; Department of Oncology and Metabolism, University of Sheffield, Medical School, Beech Hill Road, Sheffield S10 2RX, UK.
  • Zeng F; Department of Oncology and Metabolism, University of Sheffield, Medical School, Beech Hill Road, Sheffield S10 2RX, UK.
  • Carrasco G; Department of Oncology and Metabolism, University of Sheffield, Medical School, Beech Hill Road, Sheffield S10 2RX, UK.
  • Meurisse S; Galapagos SASU, 102 Avenue Gaston Roussel, 93230 Romainville, France.
  • Li B; Department of Oncology and Metabolism, University of Sheffield, Medical School, Beech Hill Road, Sheffield S10 2RX, UK.
  • Sophocleous A; Department of Life Sciences, School of Sciences, European University Cyprus, 6 Diogenes Street, 1516 Nicosia, Cyprus.
  • Sparatore A; University of Milano, Department of Pharmaceutical Science, Milan, Italy.
  • Baeuerle T; Institute of Radiology, Friedrich-Alexander-Universität Erlangen-Nürnberg and Universitätsklinikum, Erlangen, Bayern, Germany.
  • Vukicevic S; Department of Anatomy, Medical School, University of Zagreb, Zagreb, Croatia.
  • Auberval M; Galapagos SASU, 102 Avenue Gaston Roussel, 93230 Romainville, France.
  • Mollat P; Galapagos SASU, 102 Avenue Gaston Roussel, 93230 Romainville, France.
  • Bozec A; Department of Internal Medicine, 3-Rheumatology and Immunology, Friedrich-Alexander University Erlangen-Nürnberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany.
  • Idris AI; Department of Oncology and Metabolism, University of Sheffield, Medical School, Beech Hill Road, Sheffield S10 2RX, UK; Bone and Cancer Group, Edinburgh Cancer Research Centre, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, EH4 2XR, UK. Electronic address: aymen.idris@she
Biochem Pharmacol ; 195: 114869, 2022 01.
Article en En | MEDLINE | ID: mdl-34896056
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Osteólisis / Antígenos CD40 / Factor 6 Asociado a Receptor de TNF / Antiinflamatorios Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Biochem Pharmacol Año: 2022 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Osteólisis / Antígenos CD40 / Factor 6 Asociado a Receptor de TNF / Antiinflamatorios Tipo de estudio: Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: Biochem Pharmacol Año: 2022 Tipo del documento: Article País de afiliación: Reino Unido