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A structurally engineered fatty acid, icosabutate, suppresses liver inflammation and fibrosis in NASH.
Fraser, David A; Wang, Xiaoyu; Lund, Jenny; Nikolic, Natasa; Iruarrizaga-Lejarreta, Marta; Skjaeret, Tore; Alonso, Cristina; Kastelein, John J P; Rustan, Arild C; Kim, Yong Ook; Schuppan, Detlef.
Afiliación
  • Fraser DA; NorthSea Therapeutics, Amsterdam, The Netherlands.
  • Wang X; Institute of Translational Immunology and Research Center for Immune Therapy, University Medical Center, Mainz, Germany.
  • Lund J; Section for Pharmacology and Pharmaceutical Biosciences, Department of Pharmacy, University of Oslo, Norway.
  • Nikolic N; Section for Pharmacology and Pharmaceutical Biosciences, Department of Pharmacy, University of Oslo, Norway.
  • Iruarrizaga-Lejarreta M; OWL Metabolomics, Parque Tecnológico de Bizkaia, Derio, Spain.
  • Skjaeret T; NorthSea Therapeutics, Amsterdam, The Netherlands.
  • Alonso C; OWL Metabolomics, Parque Tecnológico de Bizkaia, Derio, Spain.
  • Kastelein JJP; Department of Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
  • Rustan AC; Section for Pharmacology and Pharmaceutical Biosciences, Department of Pharmacy, University of Oslo, Norway.
  • Kim YO; Institute of Translational Immunology and Research Center for Immune Therapy, University Medical Center, Mainz, Germany.
  • Schuppan D; Institute of Translational Immunology and Research Center for Immune Therapy, University Medical Center, Mainz, Germany; Division of Gastroenterology, Beth Israel Deaconess Medical Center, Boston, MA, USA. Electronic address: detlef.schuppan@unimedizin-mainz.de.
J Hepatol ; 76(4): 800-811, 2022 Apr.
Article en En | MEDLINE | ID: mdl-34915054
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Ácidos Grasos Omega-3 / Enfermedad del Hígado Graso no Alcohólico / Hepatitis Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Animals / Humans Idioma: En Revista: J Hepatol Asunto de la revista: GASTROENTEROLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Países Bajos
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Ácidos Grasos Omega-3 / Enfermedad del Hígado Graso no Alcohólico / Hepatitis Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Animals / Humans Idioma: En Revista: J Hepatol Asunto de la revista: GASTROENTEROLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Países Bajos