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Targeting Ribonucleotide Reductase Induces Synthetic Lethality in PP2A-Deficient Uterine Serous Carcinoma.
O'Connor, Caitlin M; Taylor, Sarah E; Miller, Kathryn M; Hurst, Lauren; Haanen, Terrance J; Suhan, Tahra K; Zawacki, Kaitlin P; Noto, Fallon K; Trako, Jonida; Mohan, Arathi; Sangodkar, Jaya; Zamarin, Dmitriy; DiFeo, Analisa; Narla, Goutham.
Afiliación
  • O'Connor CM; Division of Genetic Medicine, Department of Internal Medicine, The University of Michigan, Ann Arbor, Michigan.
  • Taylor SE; Rogel Cancer Center, The University of Michigan Health, Ann Arbor, Michigan.
  • Miller KM; Department of Pathology, Case Western Reserve University, Cleveland, Ohio.
  • Hurst L; Department of Surgery, Memorial Sloan Kettering Cancer Center, New York City, New York.
  • Haanen TJ; Division of Genetic Medicine, Department of Internal Medicine, The University of Michigan, Ann Arbor, Michigan.
  • Suhan TK; Rogel Cancer Center, The University of Michigan Health, Ann Arbor, Michigan.
  • Zawacki KP; Department of Cancer Biology, The University of Michigan, Ann Arbor, Michigan.
  • Noto FK; Division of Genetic Medicine, Department of Internal Medicine, The University of Michigan, Ann Arbor, Michigan.
  • Trako J; Division of Genetic Medicine, Department of Internal Medicine, The University of Michigan, Ann Arbor, Michigan.
  • Mohan A; Hera BioLabs Inc., Lexington, Kentucky.
  • Sangodkar J; Division of Genetic Medicine, Department of Internal Medicine, The University of Michigan, Ann Arbor, Michigan.
  • Zamarin D; Division of Genetic Medicine, Department of Internal Medicine, The University of Michigan, Ann Arbor, Michigan.
  • DiFeo A; Division of Genetic Medicine, Department of Internal Medicine, The University of Michigan, Ann Arbor, Michigan.
  • Narla G; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York City, New York.
Cancer Res ; 82(4): 721-733, 2022 02 15.
Article en En | MEDLINE | ID: mdl-34921012

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Ribonucleótido Reductasas / Neoplasias Uterinas / Cistadenocarcinoma Seroso / Proteína Fosfatasa 2 / Mutaciones Letales Sintéticas Límite: Animals / Female / Humans Idioma: En Revista: Cancer Res Año: 2022 Tipo del documento: Article

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Ribonucleótido Reductasas / Neoplasias Uterinas / Cistadenocarcinoma Seroso / Proteína Fosfatasa 2 / Mutaciones Letales Sintéticas Límite: Animals / Female / Humans Idioma: En Revista: Cancer Res Año: 2022 Tipo del documento: Article