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EGFR-D770>GY and Other Rare EGFR Exon 20 Insertion Mutations with a G770 Equivalence Are Sensitive to Dacomitinib or Afatinib and Responsive to EGFR Exon 20 Insertion Mutant-Active Inhibitors in Preclinical Models and Clinical Scenarios.
Kobayashi, Ikei S; Viray, Hollis; Rangachari, Deepa; Kobayashi, Susumu S; Costa, Daniel B.
Afiliación
  • Kobayashi IS; Department of Medicine, Division of Medical Oncology, Harvard Medical School, Boston, MA 02215, USA.
  • Viray H; Department of Medicine, Division of Medical Oncology, Harvard Medical School, Boston, MA 02215, USA.
  • Rangachari D; Department of Medicine, Division of Medical Oncology, Harvard Medical School, Boston, MA 02215, USA.
  • Kobayashi SS; Department of Medicine, Division of Medical Oncology, Harvard Medical School, Boston, MA 02215, USA.
  • Costa DB; Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Division of Translational Genomics, Kashiwa 277-8577, Japan.
Cells ; 10(12)2021 12 17.
Article en En | MEDLINE | ID: mdl-34944068
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Exones / Mutagénesis Insercional / Inhibidores de Proteínas Quinasas / Quinazolinonas / Receptores ErbB / Afatinib / Mutación Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Cells Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Exones / Mutagénesis Insercional / Inhibidores de Proteínas Quinasas / Quinazolinonas / Receptores ErbB / Afatinib / Mutación Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Cells Año: 2021 Tipo del documento: Article País de afiliación: Estados Unidos