Purinergic modulation of the immune response to infections.
Purinergic Signal
; 18(1): 93-113, 2022 03.
Article
en En
| MEDLINE
| ID: mdl-34997903
ABSTRACT
Infectious diseases are caused by the invasion of pathogenic microorganisms such as fungi, bacteria, viruses, and parasites. After infection, disease progression relies on the complex interplay between the host immune response and the microorganism evasion strategies. The host's survival depends on its ability to mount an efficient protective anti-microbial response to accomplish pathogen clearance while simultaneously preventing tissue injury by keeping under control the excessive inflammatory process. The purinergic system has the dual function of regulating the immune response and triggering effector antimicrobial mechanisms. This review provides an overview of the current knowledge of the modulation of innate and adaptive immunity driven by the purinergic system during parasitic, bacterial and viral infections.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Parásitos
/
Inmunidad Innata
Límite:
Animals
Idioma:
En
Revista:
Purinergic Signal
Año:
2022
Tipo del documento:
Article
País de afiliación:
Argentina