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Synthesis, radiolabeling, and evaluation of a potent ß-site APP cleaving enzyme (BACE1) inhibitor for PET imaging of BACE1 in vivo.
Pan, Lili; He, Qian; Wu, Yi; Zhang, Ni; Cai, Huawei; Yang, Bo; Wang, Yuxi; Li, Yunchun; Wu, Xiaoai.
Afiliación
  • Pan L; Department of Nuclear Medicine, Laboratory of Clinical Nuclear Medicine, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu 610041, China.
  • He Q; Department of Emergency, West China Hospital, Sichuan University, Chengdu 610000, Sichuan, China.
  • Wu Y; Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases, Ministry of Education, Gannan Medical University, Ganzhou 341000, China.
  • Zhang N; Department of Psychiatry, West China Hospital of Sichuan University, Chengdu 610041, China.
  • Cai H; Department of Nuclear Medicine, Laboratory of Clinical Nuclear Medicine, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu 610041, China.
  • Yang B; Department of Pharmacy, Panzhihua Central Hospital, Panzhihua, Sichuan, 617067, China.
  • Wang Y; Department of Respiratory and Critical Care Medicine, West China Medical School/West China Hospital, Sichuan University, Chengdu 610000, China.
  • Li Y; Department of Nuclear Medicine, Laboratory of Clinical Nuclear Medicine, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu 610041, China; Department of Nuclear Medicine, The Second People's Hospital of Yibin, Yibin 644000, Sichuan, China. Electronic a
  • Wu X; Department of Nuclear Medicine, Laboratory of Clinical Nuclear Medicine, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu 610041, China. Electronic address: xiaoai.wu@hotmail.com.
Bioorg Med Chem Lett ; 59: 128543, 2022 03 01.
Article en En | MEDLINE | ID: mdl-35031452
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Ácido Aspártico Endopeptidasas / Tomografía de Emisión de Positrones / Inhibidores Enzimáticos / Quinazolinonas / Secretasas de la Proteína Precursora del Amiloide Límite: Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2022 Tipo del documento: Article País de afiliación: China
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Ácido Aspártico Endopeptidasas / Tomografía de Emisión de Positrones / Inhibidores Enzimáticos / Quinazolinonas / Secretasas de la Proteína Precursora del Amiloide Límite: Humans Idioma: En Revista: Bioorg Med Chem Lett Asunto de la revista: BIOQUIMICA / QUIMICA Año: 2022 Tipo del documento: Article País de afiliación: China