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Inhibition of EZH2 transactivation function sensitizes solid tumors to genotoxic stress.
Liao, Yiji; Chen, Chen-Hao; Xiao, Tengfei; de la Peña Avalos, Bárbara; Dray, Eloise V; Cai, Changmeng; Gao, Shuai; Shah, Neel; Zhang, Zhao; Feit, Avery; Xue, Pengya; Liu, Zhijie; Yang, Mei; Lee, Ji Hoon; Xu, Han; Li, Wei; Mei, Shenglin; Pierre, Roodolph S; Shu, Shaokun; Fei, Teng; Duarte, Melissa; Zhao, Jin; Bradner, James E; Polyak, Kornelia; Kantoff, Philip W; Long, Henry; Balk, Steven P; Liu, X Shirley; Brown, Myles; Xu, Kexin.
Afiliación
  • Liao Y; Department of Molecular Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229.
  • Chen CH; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, MA 02115.
  • Xiao T; Department of Data Science, Dana-Farber Cancer Institute, Boston, MA 02115.
  • de la Peña Avalos B; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA 02115.
  • Dray EV; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, MA 02115.
  • Cai C; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115.
  • Gao S; Department of Biochemistry and Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229.
  • Shah N; Department of Biochemistry and Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229.
  • Zhang Z; Center for Personalized Cancer Therapy, University of Massachusetts, Boston, MA 02125.
  • Feit A; Center for Personalized Cancer Therapy, University of Massachusetts, Boston, MA 02125.
  • Xue P; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, MA 02115.
  • Liu Z; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115.
  • Yang M; Department of Molecular Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229.
  • Lee JH; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, MA 02115.
  • Xu H; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115.
  • Li W; Department of Molecular Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229.
  • Mei S; Department of Molecular Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229.
  • Pierre RS; Department of Molecular Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229.
  • Shu S; Department of Molecular Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229.
  • Fei T; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, MA 02115.
  • Duarte M; Department of Data Science, Dana-Farber Cancer Institute, Boston, MA 02115.
  • Zhao J; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, MA 02115.
  • Bradner JE; Department of Data Science, Dana-Farber Cancer Institute, Boston, MA 02115.
  • Polyak K; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, MA 02115.
  • Kantoff PW; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115.
  • Long H; Biological and Biomedical Science Program, Harvard Medical School, Boston, MA 02115.
  • Balk SP; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, MA 02115.
  • Liu XS; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115.
  • Brown M; Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, MA 02115.
  • Xu K; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115.
Proc Natl Acad Sci U S A ; 119(3)2022 01 18.
Article en En | MEDLINE | ID: mdl-35031563
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Daño del ADN / Activación Transcripcional / Proteína Potenciadora del Homólogo Zeste 2 Tipo de estudio: Prognostic_studies Límite: Humans / Male Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2022 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Daño del ADN / Activación Transcripcional / Proteína Potenciadora del Homólogo Zeste 2 Tipo de estudio: Prognostic_studies Límite: Humans / Male Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2022 Tipo del documento: Article