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CD40L-armed oncolytic herpes simplex virus suppresses pancreatic ductal adenocarcinoma by facilitating the tumor microenvironment favorable to cytotoxic T cell response in the syngeneic mouse model.
Wang, Ruikun; Chen, Jingru; Wang, Wei; Zhao, Zhuoqian; Wang, Haoran; Liu, Shiyu; Li, Fan; Wan, Yajuan; Yin, Jie; Wang, Rui; Li, Yuanke; Zhang, Cuizhu; Zhang, Hongkai; Cao, Youjia.
Afiliación
  • Wang R; Tianjin Key Laboratory of Protein Sciences, Department of Biochemistry and Molecular Biology, College of Life Sciences, Nankai University, Tianjin, China.
  • Chen J; Frontier Science Center for Cell Responses, College of Life Sciences, Nankai University, Tianjin, China.
  • Wang W; Tianjin Key Laboratory of Protein Sciences, Department of Biochemistry and Molecular Biology, College of Life Sciences, Nankai University, Tianjin, China.
  • Zhao Z; Nankai International Advanced Research Institute (Shenzhen Futian), Nankai University, Shenzhen, China.
  • Wang H; Shanghai Institute for Advanced Immunochemical Studies, ShanghaiTech University, Shanghai, China.
  • Liu S; Tianjin Key Laboratory of Protein Sciences, Department of Biochemistry and Molecular Biology, College of Life Sciences, Nankai University, Tianjin, China.
  • Li F; Tianjin Key Laboratory of Protein Sciences, Department of Biochemistry and Molecular Biology, College of Life Sciences, Nankai University, Tianjin, China.
  • Wan Y; Tianjin Key Laboratory of Protein Sciences, Department of Biochemistry and Molecular Biology, College of Life Sciences, Nankai University, Tianjin, China.
  • Yin J; State Key Laboratory of Medicinal Chemical Biology and College of Life Sciences, Nankai University, Tianjin, China.
  • Wang R; Tianjin Key Laboratory of Protein Sciences, Department of Biochemistry and Molecular Biology, College of Life Sciences, Nankai University, Tianjin, China.
  • Li Y; State Key Laboratory of Medicinal Chemical Biology and College of Life Sciences, Nankai University, Tianjin, China.
  • Zhang C; Tianjin Key Laboratory of Protein Sciences, Department of Biochemistry and Molecular Biology, College of Life Sciences, Nankai University, Tianjin, China.
  • Zhang H; Department of Immunology, Tianjin Medical University, Tianjin, China.
  • Cao Y; Tianjin Key Laboratory of Protein Sciences, Department of Biochemistry and Molecular Biology, College of Life Sciences, Nankai University, Tianjin, China.
J Immunother Cancer ; 10(1)2022 01.
Article en En | MEDLINE | ID: mdl-35086948
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Linfocitos T Citotóxicos / Simplexvirus / Carcinoma Ductal Pancreático / Ligando de CD40 / Viroterapia Oncolítica / Microambiente Tumoral Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Immunother Cancer Año: 2022 Tipo del documento: Article País de afiliación: China
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Linfocitos T Citotóxicos / Simplexvirus / Carcinoma Ductal Pancreático / Ligando de CD40 / Viroterapia Oncolítica / Microambiente Tumoral Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Immunother Cancer Año: 2022 Tipo del documento: Article País de afiliación: China