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Bullying in clinical high risk for psychosis participants from the NAPLS-3 cohort.
Braun, Amy; Liu, Lu; Bearden, Carrie E; Cadenhead, Kristin S; Cornblatt, Barbara A; Keshavan, Matcheri; Mathalon, Daniel H; McGlashan, Thomas H; Perkins, Diana O; Seidman, Larry J; Stone, William; Tsuang, Ming T; Walker, Elaine F; Woods, Scott W; Cannon, Tyrone D; Addington, Jean.
Afiliación
  • Braun A; Department of Psychiatry, Hotchkiss Brain Institute, University of Calgary, 3280 Hospital Drive NW, Calgary, AB, T2N 4Z6, Canada.
  • Liu L; Department of Psychiatry, Hotchkiss Brain Institute, University of Calgary, 3280 Hospital Drive NW, Calgary, AB, T2N 4Z6, Canada.
  • Bearden CE; Departments of Psychiatry and Biobehavioral Sciences and Psychology, Semel Institute for Neuroscience and Human Behavior, UCLA, Los Angeles, CA, USA.
  • Cadenhead KS; Department of Psychiatry, UCSD, San Diego, CA, USA.
  • Cornblatt BA; Department of Psychiatry, Zucker Hillside Hospital, Long Island, NY, USA.
  • Keshavan M; Department of Psychiatry, Harvard Medical School at Beth Israel Deaconess Medical Center and Massachusetts General Hospital, Boston, MA, USA.
  • Mathalon DH; Department of Psychiatry, UCSF, and SFVA Medical Center, San Francisco, CA, USA.
  • McGlashan TH; Department of Psychiatry, Yale University, New Haven, CT, USA.
  • Perkins DO; Department of Psychiatry, University of North Carolina, Chapel Hill, NC, USA.
  • Seidman LJ; Department of Psychiatry, Harvard Medical School at Beth Israel Deaconess Medical Center and Massachusetts General Hospital, Boston, MA, USA.
  • Stone W; Department of Psychiatry, Harvard Medical School at Beth Israel Deaconess Medical Center and Massachusetts General Hospital, Boston, MA, USA.
  • Tsuang MT; Department of Psychiatry, UCSD, San Diego, CA, USA.
  • Walker EF; Institute of Genomic Medicine, University of California, La Jolla, CA, USA.
  • Woods SW; Departments of Psychology and Psychiatry, Emory University, Atlanta, GA, USA.
  • Cannon TD; Department of Psychiatry, Yale University, New Haven, CT, USA.
  • Addington J; Department of Psychology, Yale University, New Haven, CT, USA.
Soc Psychiatry Psychiatr Epidemiol ; 57(7): 1379-1388, 2022 Jul.
Article en En | MEDLINE | ID: mdl-35113189
ABSTRACT

PURPOSE:

Bullying is associated with a heightened risk for poor outcomes, including psychosis. This study aimed to replicate previous findings on bullying prevalence in clinical high-risk (CHR) individuals, to assess the longitudinal course of clinical and functional variables between bullied and non-bullied CHR and the association of bullying with premorbid functioning, clinical outcome, transition to psychosis and risk of violence.

METHODS:

The sample consisted of 691 CHR participants and 96 healthy controls. Participants reported whether they had experienced bullying and how long it had lasted. Assessments included DSM-5 diagnoses, attenuated psychotic symptoms, negative symptoms, social and role functioning, depression, stress, premorbid functioning, and risk of violence. The bullied and non-bullied CHR groups were compared at baseline and further longitudinally on clinical and functioning variables and transition to psychosis.

RESULTS:

Bullying was more prevalent among CHR individuals than healthy controls. Bullied CHR had a higher prevalence of PTSD and more severe depression and stress at baseline than non-bullied CHR. There was no impact of bullying on clinical and functional variables over time. Bullying was not related to final clinical status or transition to psychosis. However, bullied participants had poorer premorbid functioning and a greater risk of violence.

CONCLUSION:

While bullying may not impact the likelihood of CHR individuals to transition to psychosis, it may be a risk factor for development of the at-risk state and may be related to a greater risk of violence. Future studies should consider bullying perpetration among CHR individuals.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Trastornos Psicóticos / Acoso Escolar Tipo de estudio: Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Soc Psychiatry Psychiatr Epidemiol Asunto de la revista: CIENCIAS SOCIAIS / EPIDEMIOLOGIA / PSIQUIATRIA Año: 2022 Tipo del documento: Article País de afiliación: Canadá

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Trastornos Psicóticos / Acoso Escolar Tipo de estudio: Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: Soc Psychiatry Psychiatr Epidemiol Asunto de la revista: CIENCIAS SOCIAIS / EPIDEMIOLOGIA / PSIQUIATRIA Año: 2022 Tipo del documento: Article País de afiliación: Canadá