Identification of a novel cationic glycolipid in Streptococcus agalactiae that contributes to brain entry and meningitis.

Joyce, Luke R; Manzer, Haider S; da C Mendonça, Jéssica; Villarreal, Ricardo; Nagao, Prescilla E; Doran, Kelly S; Palmer, Kelli L; Guan, Ziqiang

Joyce, Luke R; Manzer, Haider S; da C Mendonça, Jéssica; Villarreal, Ricardo; Nagao, Prescilla E; Doran, Kelly S; Palmer, Kelli L; Guan, Ziqiang.

Afiliación

Joyce LR; Department of Biological Sciences, The University of Texas at Dallas, Richardson, Texas, United States of America.
Manzer HS; Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, United States of America.
da C Mendonça J; Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, United States of America.
Villarreal R; Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, United States of America.
Nagao PE; Rio de Janeiro State University, Roberto Alcântara Gomes Biology Institute, Rio de Janeiro, Rio de Janeiro, Brazil.
Doran KS; Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, United States of America.
Palmer KL; Rio de Janeiro State University, Roberto Alcântara Gomes Biology Institute, Rio de Janeiro, Rio de Janeiro, Brazil.
Guan Z; Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, United States of America.

PLoS Biol ; 20(2): e3001555, 2022 02.

Article en En | MEDLINE | ID: mdl-35180210

Asunto(s)

Barrera Hematoencefálica/metabolismo; Encéfalo/metabolismo; Glucolípidos/metabolismo; Meningitis/metabolismo; Streptococcus agalactiae/metabolismo; Aminoaciltransferasas/genética; Aminoaciltransferasas/metabolismo; Animales; Proteínas Bacterianas/genética; Proteínas Bacterianas/metabolismo; Transporte Biológico/genética; Cationes/química; Cromatografía Liquida/métodos; Glucolípidos/química; Humanos; Masculino; Ratones; Mutación; Espectrometría de Masa por Ionización de Electrospray/métodos; Streptococcus agalactiae/genética; Espectrometría de Masas en Tándem/métodos

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Streptococcus agalactiae / Encéfalo / Barrera Hematoencefálica / Glucolípidos / Meningitis Tipo de estudio: Diagnostic_studies Límite: Animals / Humans / Male Idioma: En Revista: PLoS Biol Asunto de la revista: BIOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos

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