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Novel mutation in hexokinase 2 confers resistance to 2-deoxyglucose by altering protein dynamics.
Hellemann, Erich; Walker, Jennifer L; Lesko, Mitchell A; Chandrashekarappa, Dakshayini G; Schmidt, Martin C; O'Donnell, Allyson F; Durrant, Jacob D.
Afiliación
  • Hellemann E; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
  • Walker JL; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
  • Lesko MA; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
  • Chandrashekarappa DG; University of Pittsburgh School of Medicine, Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
  • Schmidt MC; University of Pittsburgh School of Medicine, Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
  • O'Donnell AF; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
  • Durrant JD; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
PLoS Comput Biol ; 18(3): e1009929, 2022 03.
Article en En | MEDLINE | ID: mdl-35235554

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Desoxiglucosa / Hexoquinasa Idioma: En Revista: PLoS Comput Biol Asunto de la revista: BIOLOGIA / INFORMATICA MEDICA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Desoxiglucosa / Hexoquinasa Idioma: En Revista: PLoS Comput Biol Asunto de la revista: BIOLOGIA / INFORMATICA MEDICA Año: 2022 Tipo del documento: Article País de afiliación: Estados Unidos