Post-vaccination aluminium granulomas in children. / Aluminiumsgranulomer etter barnevaksinasjon.
Tidsskr Nor Laegeforen
; 142(4)2022 03 01.
Article
en En, Nor
| MEDLINE
| ID: mdl-35239278
ABSTRACT
BACKGROUND:
Persistent itching subcutaneous granulomas related to aluminium-containing vaccines are poorly recognised in health care. They are often associated with aluminium hypersensitivity. CASE PRESENTATION An intensely itching subcutaneous nodule appeared on the left thigh of a 17-month-old girl at the injection site for an aluminium adsorbed diphtheria-tetanus-pertussis-polio-HiB vaccine given at 3, 5 and 12 months. Ultrasound suggested a vascular malformation among other differential diagnoses. An MR investigation under general anaesthesia was planned, but the diagnosis was confirmed prior to this by a positive epicutaneous test with aluminium.INTERPRETATION:
Despite a typical history of an itchy vaccination granuloma, the child underwent a thorough hospital workup to rule out malignancy. The diagnosis was delayed for two years. Vaccination granulomas have a good prognosis but can persist for many years. It is important to recognise the condition early in primary health care to avoid unnecessary anxiety and investigations.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Vacuna contra Difteria, Tétanos y Tos Ferina
/
Aluminio
Tipo de estudio:
Prognostic_studies
Límite:
Child
/
Female
/
Humans
/
Infant
Idioma:
En
/
Nor
Revista:
Tidsskr Nor Laegeforen
Año:
2022
Tipo del documento:
Article