Radiomics with 3-dimensional magnetic resonance fingerprinting: influence of dictionary design on repeatability and reproducibility of radiomic features.
Eur Radiol
; 32(7): 4791-4800, 2022 Jul.
Article
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| MEDLINE
| ID: mdl-35304637
ABSTRACT
OBJECTIVES:
We aimed to investigate the influence of magnetic resonance fingerprinting (MRF) dictionary design on radiomic features using in vivo human brain scans.METHODS:
Scan-rescans of three-dimensional MRF and conventional T1-weighted imaging were performed on 21 healthy volunteers (9 males and 12 females; mean age, 41.3 ± 14.6 years; age range, 22-72 years). Five patients with multiple sclerosis (3 males and 2 females; mean age, 41.2 ± 7.3 years; age range, 32-53 years) were also included. MRF data were reconstructed using various dictionaries with different step sizes. First- and second-order radiomic features were extracted from each dataset. Intra-dictionary repeatability and inter-dictionary reproducibility were evaluated using intraclass correlation coefficients (ICCs). Features with ICCs > 0.90 were considered acceptable. Relative changes were calculated to assess inter-dictionary biases.RESULTS:
The overall scan-rescan ICCs of MRF-based radiomics ranged from 0.86 to 0.95, depending on dictionary step size. No significant differences were observed in the overall scan-rescan repeatability of MRF-based radiomic features and conventional T1-weighted imaging (p = 1.00). Intra-dictionary repeatability was insensitive to dictionary step size differences. MRF-based radiomic features varied among dictionaries (overall ICC for inter-dictionary reproducibility, 0.62-0.99), especially when step sizes were large. First-order and gray level co-occurrence matrix features were the most reproducible feature classes among different step size dictionaries. T1 map-derived radiomic features provided higher repeatability and reproducibility among dictionaries than those obtained with T2 maps.CONCLUSION:
MRF-based radiomic features are highly repeatable in various dictionary step sizes. Caution is warranted when performing MRF-based radiomics using datasets containing maps generated from different dictionaries. KEY POINTS ⢠MRF-based radiomic features are highly repeatable in various dictionary step sizes. ⢠Use of different MRF dictionaries may result in variable radiomic features, even when the same MRF acquisition data are used. ⢠Caution is needed when performing radiomic analysis using data reconstructed from different dictionaries.Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Procesamiento de Imagen Asistido por Computador
/
Imagen por Resonancia Magnética
Límite:
Adult
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Aged
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Female
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Humans
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Middle aged
Idioma:
En
Revista:
Eur Radiol
Asunto de la revista:
RADIOLOGIA
Año:
2022
Tipo del documento:
Article
País de afiliación:
Japón