Sp7 Transgenic Mice with a Markedly Impaired Lacunocanalicular Network Induced Sost and Reduced Bone Mass by Unloading.

Moriishi, Takeshi; Ito, Takuro; Fukuyama, Ryo; Qin, Xin; Komori, Hisato; Kaneko, Hitomi; Matsuo, Yuki; Yoshida, Noriaki; Komori, Toshihisa

Moriishi, Takeshi; Ito, Takuro; Fukuyama, Ryo; Qin, Xin; Komori, Hisato; Kaneko, Hitomi; Matsuo, Yuki; Yoshida, Noriaki; Komori, Toshihisa.

Afiliación

Moriishi T; Department of Cell Biology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8588, Japan.
Ito T; Basic and Translational Research Center for Hard Tissue Disease, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8588, Japan.
Fukuyama R; Department of Orthodontics and Dentofacial Orthopedics, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8588, Japan.
Qin X; Laboratory of Pharmacology, Hiroshima International University, Kure 737-0112, Japan.
Komori H; Basic and Translational Research Center for Hard Tissue Disease, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8588, Japan.
Kaneko H; Japan Society for the Promotion of Science International Research Fellow, Tokyo 102-0083, Japan.
Matsuo Y; Basic and Translational Research Center for Hard Tissue Disease, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8588, Japan.
Yoshida N; Basic and Translational Research Center for Hard Tissue Disease, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8588, Japan.
Komori T; Basic and Translational Research Center for Hard Tissue Disease, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8588, Japan.

Int J Mol Sci ; 23(6)2022 Mar 15.

Article en En | MEDLINE | ID: mdl-35328592

Asunto(s)

Resorción Ósea; Osteocitos; Proteínas Adaptadoras Transductoras de Señales/genética; Proteínas Adaptadoras Transductoras de Señales/metabolismo; Animales; Densidad Ósea; Resorción Ósea/metabolismo; Huesos/metabolismo; Femenino; Masculino; Ratones; Ratones Transgénicos; Osteoblastos/metabolismo; Osteocitos/metabolismo; Factor de Transcripción Sp7/metabolismo

Palabras clave

Sost; Sp7; apoptosis; bone formation; bone resorption; canaliculus; lacunocanalicular network; mechanical stress; osteocyte; unloading

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Osteocitos / Resorción Ósea Límite: Animals Idioma: En Revista: Int J Mol Sci Año: 2022 Tipo del documento: Article País de afiliación: Japón

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