COVID-19 Vaccines and Hyperglycemia-Is There a Need for Postvaccination Surveillance?
Vaccines (Basel)
; 10(3)2022 Mar 16.
Article
en En
| MEDLINE
| ID: mdl-35335086
ABSTRACT
The COVID-19 vaccines currently in use have undoubtedly played the most significant role in combating the SARS-CoV-2 virus and reducing disease severity and the risk of death among those affected, especially among those with pre-existing conditions, such as diabetes. The management of blood glucose levels has become critical in the context of the COVID-19 pandemic, where data show two- to threefold higher intensive care hospital admissions and more than twice the mortality rate among diabetic COVID-19 patients when compared with their nondiabetic counterparts. Furthermore, new-onset diabetes and severe hyperglycemia-related complications, such as hyperosmolar hyperglycemic syndrome (HHS) and diabetic ketoacidosis (DKA), were reported in COVID-19 patients. However, irrespective of the kind of vaccine and dosage number, possible vaccination-induced hyperglycemia and associated complications were reported among vaccinated individuals. The current article summarizes the available case reports on COVID-19 vaccination-induced hyperglycemia, the possible molecular mechanism responsible for this phenomenon, and the outstanding questions that need to be addressed and discusses the need to identify at-risk individuals and promote postvaccination monitoring/surveillance among at-risk individuals.
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1
Colección:
01-internacional
Banco de datos:
MEDLINE
Tipo de estudio:
Screening_studies
Idioma:
En
Revista:
Vaccines (Basel)
Año:
2022
Tipo del documento:
Article
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