Atypical chemokine receptor 3 induces colorectal tumorigenesis in mice by promoting ß-arrestin-NOLC1-fibrillarin-dependent rRNA biogenesis.

Yang, Juan; Miao, Rong-Rong; Li, Ya-Nan; Pan, Ting; Wu, Shu-Hua; Qu, Xian-Jun; Cui, Shu-Xiang

Yang, Juan; Miao, Rong-Rong; Li, Ya-Nan; Pan, Ting; Wu, Shu-Hua; Qu, Xian-Jun; Cui, Shu-Xiang.

Afiliación

Yang J; Beijing Key Laboratory of Environmental Toxicology, Department of Toxicology and Sanitary Chemistry, School of Public Health, Capital Medical University, Beijing, 100069, China.
Miao RR; Department of Comprehensive Ward, Affiliated Hospital of Guizhou Medical University, Guiyang, 550004, China.
Li YN; Department of Pharmacology, School of Basic Medical Sciences, Capital Medical University, Beijing, 100069, China.
Pan T; Beijing Key Laboratory of Environmental Toxicology, Department of Toxicology and Sanitary Chemistry, School of Public Health, Capital Medical University, Beijing, 100069, China.
Wu SH; Beijing Key Laboratory of Environmental Toxicology, Department of Toxicology and Sanitary Chemistry, School of Public Health, Capital Medical University, Beijing, 100069, China.
Qu XJ; Department of Pathology, Hospital of Bin Zhou Medical College, Binzhou, 256603, China.
Cui SX; Department of Pharmacology, School of Basic Medical Sciences, Capital Medical University, Beijing, 100069, China.

Acta Pharmacol Sin ; 43(11): 2967-2976, 2022 Nov.

Article en En | MEDLINE | ID: mdl-35365782

Asunto(s)

Transformación Celular Neoplásica; Neoplasias Colorrectales; Receptores CXCR; Animales; Humanos; Ratones; beta-Arrestina 1/genética; beta-Arrestina 1/metabolismo; beta-Arrestinas/metabolismo; Carcinogénesis/genética; Transformación Celular Neoplásica/genética; Quimiocina CXCL12; Neoplasias Colorrectales/genética; Ratones Transgénicos; Proteínas Nucleares/genética; Fosfoproteínas/metabolismo; Receptores CXCR/metabolismo

Palabras clave

ACKR3; NOLC1; Villin-ACKR3 transgenic mice; fibrillarin; ribosome biogenesis; tumorigenesis

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Transformación Celular Neoplásica / Receptores CXCR Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Acta Pharmacol Sin Asunto de la revista: FARMACOLOGIA Año: 2022 Tipo del documento: Article País de afiliación: China

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